Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09506 Pf-477736 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 183 STAT5B; SETDB1; PPARD; PMF1; CBX4; ZNF692; ZNF44; ETV7; ZNF16; TEAD3; ADRB2; TRIM25; SUPT7L; THAP3; COPS5; MLX; HOXB5; TAF12; GTF2F1; THRAP3; REXO4; ATN1; ZNF131; ZIC1; ZNF562; CDX1; HOXB6; IL16; SCMH1; RARA; MED27; TERF2; HMGXB3; ZBTB43; ZNF91; PTRF; RING1; TAF1C; CCDC59; TRPS1; EGR1; TRIM22; TTF1; NFIX; PRDM1; KAT6B; TGIF2; HOXB13; NR1H2; MAFF; UIMC1; PAXBP1; ZNF175; BARX1; STAT2; HCFC2; CD3D; EZH1; PAX6; ZBTB1; BATF; TFEB; HMGB2; RAD21; HOXB2; CERS6; ZBTB48; SALL2; VPS72; YY1; KAT2B; E2F5; IRF7; MYRF; HINFP; CREB3; ZNF394; CBFA2T3; SSX1; SNAPC4; TXNIP; ARID3B; CDX2; MXI1; ZNF654; POLR3C; ZNF22; ZNF778; TWIST1; AIP; RARG; ZNF85; CHD4; TFCP2; THRA; ZNF202; IRF9; RNF141; GFI1; ZNF669; LHX3; BCL11A; MECP2; ZNF7; SMAD1; THRB; REPIN1; ZNF43; IRF8; FOXF2; ZNF331; ZBTB16; ZNF324; ZNF226; ZNF74; SPDEF; ERBB4; MKL2; LYL1; SRY; STAT4; TRIB3; IKZF1; ZFP2; ST18; HIPK2; PRRX1; ESRRG; EGR2; SOX5; PITX1; SIX6; SIAH2; ZKSCAN4; MNDA; ZNF500; MYBL1; ZNF711; NR1H3; ZBTB44; TCF7; NFATC4; ZNF273; IRF4; TFAP2A; TCF12; BTG1; CALR; ZNF124; HDAC9; BHLHE41; POU2AF1; SOHLH2; FLI1; PRDM14; KLF9; ZNF573; ZNF665; PAX5; BACH2; YBX3; TCF4; ZHX2; KLF3; MYB; SPIB; HEY1; EHF; ARNT2; BNC1; SIX3; LEF1; AEBP1; ARID5B; TOX3; TOX; ZNF589; NR4A2; CEBPA; NEUROD1; WT1; MEF2C; NFATC3
Down-regulation 89 BASP1; TSC22D2; NFIB; PPARGC1A; WWC1; MAZ; PAX8; SREBF2; WWTR1; ISL1; CTBP1; HIVEP2; NAB1; KLF12; TGFB1; KLF6; C1D; RBPMS; UBP1; SMARCA5; YAP1; ZBTB38; NPAS2; DLX2; TCF25; TCEB2; RNF4; SMARCC1; SMARCA1; HSF2; TRIM24; BBX; TSC22D1; ZNF281; HNRNPD; AHR; TRIM28; SCAND1; CREB5; BAZ1B; DNMT3B; HLTF; SMARCA2; CNBP; CBX3; ALX1; MAF; GATA6; ETS2; MEIS1; SOX4; BAZ2B; FLNA; ENO1; SUB1; AFF1; HTATIP2; YWHAB; NCOA4; PURA; NKX2-1; ZNF217; FOXJ3; MBD2; NR2F2; NFE2L3; ELF3; BCL6; NONO; SHOX2; NR2F1; PBX3; TBX3; HMGN3; ACTL6A; ZBTB18; BCL3; ERG; MAFB; ZNF302; IKBKAP; FOSB; NCOA1; CITED2; NR1D2; HOXC6; ZNF586; NR3C1; PPARG