Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09505 Pf-477736 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 590 TAF1; HMBOX1; HDAC11; TRPS1; ZNF816; ETV1; RING1; FOXJ1; RARG; ZNF75D; E2F4; PROP1; GBX1; ZNF556; CCNT1; NHLH1; HINFP; SOX2; SOX5; NRL; MYRF; TAF6L; FOXA2; TCEA2; ZNF562; SUPT3H; PRDM14; TRIM29; NR2E1; NEUROG1; ZNF91; SIRT2; LHX3; HEY1; NFIX; CEBPD; MBD1; ZNF8; SUPT7L; ATF3; PAX7; ZNF688; HEYL; CBFA2T3; MED12; ZNF444; OVOL2; CDIP1; TRIM22; AIRE; TGIF2; ARID3B; ASCL3; GATA1; HHEX; OLIG2; ZNF665; EPAS1; AFF4; TUB; RORC; ALX3; ZNF573; MAP3K10; ZNF671; ELK4; PRRX2; NR1H2; ZNF510; ZNF79; ZKSCAN3; NEUROD2; TRIB3; ZSCAN18; RAX; RFX1; NR1H3; CBX2; GRIP1; SOX21; TULP2; PPARD; ZNF667; ZNF177; LHX2; NFATC4; MAPK8IP1; HIPK2; CARF; LMX1B; PAX1; FOXF2; ZBED2; VAX2; ID4; PRRX1; E2F5; THRB; NKX3-2; RB1; SOX9; ZNF74; TCFL5; CBFA2T2; NOCT; ZNF276; NFYA; NFRKB; MED20; ZKSCAN1; ZXDB; PPARA; ZNF33B; ZNF264; ZNF131; HOXC11; SP1; ZNF701; ZNF589; ZNF415; HESX1; ALX4; POU3F3; CREM; ZNF223; ZNF331; REXO4; HIRA; ZNF778; FOXF1; RELB; ONECUT2; SCRT1; IRF9; HOXC5; ZNF239; ZNF211; GON4L; ZNF175; IKZF4; ARID5A; HIF3A; PAX6; MED17; HOXC13; HOXB1; MAML3; HEY2; KLF13; TBL1Y; ZNF253; CHD2; AFF2; HOXB13; ZNF480; DLX2; DDIT3; ZNF124; TAF4B; ETV6; ZNF133; DLX5; ZBTB17; KLF15; ZNF711; ZNF154; ZFHX2; CBL; CRX; ZNF221; ASH1L; ZIM2; TLX3; ATF5; ZNF117; ZNF606; GLI2; ZNF500; NFX1; ZBED1; IKZF1; TEF; NR5A1; ARNTL; ZBTB43; ING4; PBXIP1; PRDM13; RBPJL; NR2F6; AEBP1; ZNF749; ZNF695; ZNF10; PRDM1; AR; KLF9; EZH1; OVOL1; THRA; YAP1; SIX3; ZNF174; ZNF44; POU6F1; SRY; PRDM2; TP73; ZNF835; KAT2A; ZKSCAN8; FOXN1; RAD21; IRF7; TRIM25; GCM1; EMX1; POU6F2; ZNF263; TP63; HOXB8; TFDP3; ZNF76; E4F1; ZNF550; ZNF83; LYL1; NEUROG3; PITX3; DOT1L; ZNF132; IFNB1; EN1; HOXD1; ZNF273; AFF3; ZNF136; ESRRB; KLF5; BARX1; TAF9B; ZNF335; PTRF; NKX2-2; TRIP11; TCF3; NCOA3; TBX5; ZNF426; PROX1; ETV3; SPIB; CEBPA; TAF9; ZSCAN9; MZF1; TBX4; PRDM9; ST18; BNC1; ZNF224; PDX1; NR0B2; ZNF345; PRDM5; CCNH; GSC2; ZNF549; TSC22D3; ZNF85; ZNF93; CDX1; IRF6; CBX4; RORB; TFAP2A; PRDM10; SOX13; TDP2; PGR; TBX10; NR4A3; NKX6-1; TAF7L; SPDEF; ZNF343; MECP2; STAT4; ZNF324B; THAP3; ZXDC; CERS4; NFAT5; ZNF43; ZNF232; RFXAP; SHOX; HOXA4; TAF1C; SMAD5; TBR1; ZSCAN32; TAF12; ZBTB7C; L3MBTL1; ZNF611; BACH2; HSF4; VPS72; ZNF814; SCAI; FOXE1; ZNF682; CHD9; LDB1; SSX3; MAK; ZNF135; TFAP4; SKIL; POU4F3; BCL11A; HOXD12; FEZF2; SNAI2; ZKSCAN4; JUP; HLX; ZNF654; THAP9; PLAG1; ARL2BP; ZNF391; PAX3; NEUROG2; RXRG; ZEB1; RSF1; NR6A1; BRDT; HOXD3; MLLT1; SIX6; VENTX; HMGXB3; SOX18; MXD1; PRDM12; ZNF613; FOXD3; TSHZ2; HMX1; DCC; ZNF771; CEBPG; SALL2; TBX1; ZNF197; ZNF780B; FOXE3; MKL2; ZNF407; ZNF165; HOXC8; ZNF257; IL16; MED25; SOX14; SNAPC4; SSX7; ZNF430; ZNF442; HNF4G; DLX4; ZNF471; TULP1; TAL1; ZNF235; ID1; ZNF669; SKI; BRWD1; PEG3; ONECUT1; SOHLH2; CREBL2; ZNF507; RFX2; BARX2; LZTR1; ZNF81; CBX8; ZNF222; WHSC1L1; ZNF623; ZIC1; PAX4; KDM5D; ZNF652; SMAD9; POU2F3; SOX11; ZNF440; ZNF692; TRAF6; ZNF208; ZNF254; NFE2; ZNF350; TBX21; ZNF202; ARID3A; SOX10; ZNF214; JUN; KLF3; RFX3; PHF1; NR2C2; EGR4; ZNF141; SOX3; NANOG; ATF7; NCOA2; FOXH1; AGO2; ZNF195; ZNF675; ZNF571; ASCL2; CDK8; HES2; ZNF157; ZNF324; SOX17; ZNF287; ZNF112; GCM2; PAXBP1; CUX2; ZNF674; LZTS1; YY1; RUNX2; ZFHX4; IRF4; ZNF80; KDM4C; ZNF225; SUV39H2; GRHL2; ATOH1; ZHX2; GFI1B; MLLT10; CDX2; NR1I3; PAWR; SRCAP; ZBTB44; EYA3; HOXA1; BNC2; ZNF329; FEV; ZBTB48; ZNF334; POU3F4; IRX4; KLF8; HOXB5; MEF2C; NEUROD4; SP4; RCOR3; FOS; ZNF574; NR4A2; BPTF; NEUROD6; HDAC5; BCL6; ZBTB3; IKZF2; TFDP2; RXRA; VGLL1; GFI1; BHLHE41; SSBP2; MXI1; HOXA2; VHL; ZNF22; KLF1; REL; ZNF337; SSBP3; ZBTB16; POU1F1; ZNF160; ZNF394; ZNF362; IKZF3; CD3D; TFEC; MSX2; ZNF460; ZNF266; ZIC4; ZNF492; ZNF304; POLR3C; FOXG1; CEBPB; SSX1; PKNOX2; ERBB4; ID3; TCEA1; TAF5L; KAT2B; HIC2; ZNF467; NHLH2; EP300; ZNF134; ZFP36L2; ZNF286A; NLK; PAX5; EYA2; TCF7; ZFY; ZNF419; TAF1A; ZFP2; UTF1; ZSCAN31; PBX3; ZFP69B; NEUROD1; NR5A2; THAP11; ZNF512B; KLF2; ZIC3; MECOM; STAT2; ZNF710; SMAD1; KLF11; KLF4; TCF21; RBL2; ZNF544; ARNT2; TBX3; TCF7L2; MDM2; FLI1; EHF; MYF6; TFAP2C; CBX7; PBX1; MEIS2; TCF4; POU5F1B; ZNF551; FHL5; TXNIP; RUNX3; MYB; YBX3; IRF8; ZFP36L1; ELF3; MYBL1; SATB1; FUBP1; WT1; EGR2; INSM1; NFKB2; LIN28A; ZNF586; ZNF423; IKBKAP
Down-regulation 172 SNW1; PAX8; FHL2; MTA1; TCERG1; MAZ; TP53; PCBD1; TBL1XR1; HOXA10; NR2F2; NEDD8; TBP; NPM1; DRAP1; TSC22D2; SND1; LOXL2; BAZ1B; MTF2; SMARCA4; USP22; KAT7; ECD; SFPQ; JARID2; CITED2; ATF1; HSF2; FOXO3; MYCBP; NFIB; ZNF212; FOXJ3; CDK2; SMARCE1; MED6; PA2G4; RCOR1; HMG20B; BAZ1A; HMGB1; CRK; APEX1; FOXC1; RBBP4; RFX5; HOXC6; NRIP1; MAX; HOXB7; ERBB2; HNRNPD; HCFC1; BASP1; DNAJC2; PCGF2; HLTF; SUB1; TRIM28; NUP62; XBP1; DAXX; REST; CBX3; CTR9; UBP1; UBE2I; AATF; STAT6; HIVEP2; USF2; ZMYND8; RNF4; NFYC; HMGA1; AFF1; PATZ1; EZH2; ENO1; YWHAB; RNF10; CBFB; ELK1; BCLAF1; EDF1; SF1; POLR2A; SMARCA5; SUV39H1; ZNF410; NACA; FOSL2; ELF1; HTATIP2; ZMIZ2; PRKDC; ZNF148; RREB1; RLF; SPEN; DNMT3B; TAF10; NCOR2; PPARGC1A; KDM2A; SMARCC1; REPIN1; TCF20; FLNA; BRD8; BMI1; FOXD1; RHOA; ITGB3BP; NR3C2; SMAD3; SOX4; NRBF2; RERE; ZEB2; ELK3; WWTR1; ZNF292; XRCC6; ORC2; BTF3; CTBP1; HDAC1; MITF; SMAD2; NFE2L1; SMARCC2; CALR; PLAGL2; ASH2L; NFE2L3; ZBTB38; ARID1A; TLE1; MSX1; VGLL4; SMARCA2; EMX2; NONO; CERS6; TRIP6; SIX1; BCOR; ZBTB1; VEZF1; BRPF1; MED1; MAFB; HOXB6; FOXO1; SLC2A4RG; MLXIP; MYC; DPF2; CARHSP1; PUF60; ZNF146; PSIP1; CUX1; HMGN3; EGR3; CRY1; BCL3; CEBPZ; SAP30; NR3C1