Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09504 Pf-477736 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 268 ZNF444; CERS4; IKZF1; TRIM22; ZBTB16; TRPS1; TCEA2; EGR1; FOXO1; SOX2; ZNF654; DNMT1; JUN; KLF13; PKNOX2; NKX2-1; GMNN; E4F1; ATF3; CREB3L2; ZNF816; ZNF75D; BATF; KLF7; GATA1; MED17; LDB1; HIRA; MYNN; NAB2; CAMTA2; SAP18; SUPT7L; NFIX; ATF5; NR4A1; AFF2; CEBPD; NR1H2; AR; LHX3; IRF9; RB1; RING1; ZNF692; NRL; ZNF778; PLAG1; CEBPA; TAF5L; SPDEF; NEUROD2; TRIM24; NFIC; ZNF589; PIAS4; ZNF268; TAF1; TP63; ZNF180; ARNTL; ZNF350; ARHGAP35; FOXE1; PGR; ZBED2; TBX21; ZNF33B; ZFPM2; HOXD1; NKX3-2; FOXA2; GFI1; ZNF500; ZNF140; BCL6; TSC22D3; SOX5; CITED1; HIF3A; ZNF235; ZNF239; VAX2; ZXDC; ZNF580; TULP3; LHX2; ZSCAN9; L3MBTL1; BNC2; ZNF91; RARG; SOX10; GLI2; ETV1; WNT4; VENTX; ZNF557; PRDM14; ZNF224; CUX2; BACH2; SOX3; CDC5L; SUPT3H; ZNF211; SNAPC4; IRX4; BRD4; ING4; SRY; EZH1; ZNF573; SALL2; DDIT3; PSPC1; PRDM2; INSR; TWIST1; ZNF667; ZNF512B; POLR3C; NHLH1; TLX3; PEG3; KLF15; NCOA2; ZNF770; TLE2; HOXB5; TP73; HINFP; FEZF2; TAF5; PRDM12; HMGB3; SPIB; ZNF195; CHD2; ZBTB48; ZKSCAN4; EP300; CLOCK; PAX1; ZNF331; TCF21; KDM5D; BARX1; EGR2; TRIB3; SMARCD3; PBXIP1; CHD9; CBFA2T3; TGIF2; ZKSCAN3; NEUROD1; CBX4; JUP; CD3D; MAK; ZNF324; THRB; ZNF227; TULP1; MYB; ZBTB44; CBX7; ZNF606; EMX1; AEBP1; HIPK2; ZNF177; KAT2B; TFDP3; CSDC2; IRF6; ZNF74; BTG1; HHEX; SOX18; MYRF; NEUROG2; ZNF430; ZNF701; TULP2; GATA2; ZNF688; ZNF154; IRF7; CTBP2; PRDM10; ATF4; RORA; ZIM2; CREM; CREB1; HDAC4; HDAC5; CREBL2; SOX21; PAX5; HOXD3; PAWR; ZNF44; GATA6; ESR1; ZNF695; ARL2BP; PROX1; FOSB; MDM2; MED13; POU6F2; HIC2; STAT4; EN1; ELF5; ZNF232; ZNF467; VGLL1; E2F5; SIX3; ZFP36L1; FOS; ZNF264; OLIG2; THAP11; OVOL2; TAL1; IL16; ZIC1; RUNX3; IRF4; BCL11A; FOXF2; CEBPB; ZNF544; NANOG; ZHX2; PRRX1; HDAC9; BRD2; NR4A2; TFAP2C; KLF9; ZNF124; SOX17; MYBL1; BNC1; LEF1; ZNF611; ZNF711; TCF7L2; SOHLH2; ZNF652; CITED2; POU2AF1; MNDA; ZIC3; ERBB4; PBX3; PBX1; IRF8; ZNF665; WT1; ST18; MEIS2
Down-regulation 133 HOXA5; TSC22D2; NUP62; FOXC1; FOXO3; YBX1; TFDP1; DNMT3B; PAX8; PIAS2; HOXC10; TCERG1; RBBP4; BMI1; ELK3; HNRNPD; SFMBT1; MYCBP; ZFP64; TBL1XR1; HIVEP2; MAZ; TP53; HOXA10; RCOR1; SMAD3; TBP; CHD1; SNW1; AFF1; ZBTB38; SMARCA5; HMGA1; PDLIM1; CBFB; ELK1; BAZ2A; ENO1; RBM14; HOXC6; JARID2; RNF141; APEX1; CCNE1; XBP1; HOXB7; SIX2; TCF15; VGLL4; ATF1; RHOA; NRIP1; SMARCA4; EMX2; NEDD8; SMARCC1; HDAC7; HSBP1; USP22; ADNP2; FOXJ3; FOXD1; TAF10; BCL11B; SFPQ; WWC1; MAF; BAZ1A; MEF2A; EDF1; NPAT; RNF10; PPARGC1A; CARM1; ORC2; BAZ1B; SMAD2; MTA1; SUB1; MNAT1; BBX; YWHAB; BCLAF1; DNAJC2; KAT7; CBX3; SMAD7; HIPK3; MYCN; CTNNB1; NRBF2; TRAK1; HMGB1; MAGED1; TLE1; SCAND1; ZBTB1; TSC22D1; CALR; USF2; SIX1; ZNF468; BHLHE40; MSX1; ATF7IP; NCOA4; ELF1; MYC; NONO; ETS2; FOSL2; CRY1; HLTF; ZEB2; KLF6; PRKDC; ACTL6A; ZFHX4; MEIS1; WWTR1; CARHSP1; CTR9; SALL1; MED1; ERG; HTATIP2; TCF4; FLNA; BHLHE41; NR1D2; ARID5B; NR3C1; TOX3