Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09496 Roscovitine GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 67 KDM5A; ZNF268; SETDB1; ZKSCAN1; IFI16; HMGA2; ZNF623; HOXA11; HSF1; ZNF410; SMARCD1; ARID4B; SP140; SP140L; CDC5L; ZNF22; NFE2L3; TGFB1I1; RXRG; HOXD10; HOXD11; PLAGL1; IRF1; GATA2; MEOX2; RORA; MEIS2; CITED1; SSX1; MKL2; RHOA; ZNF34; OSR2; IRF2; BHLHE40; HOXB7; TWIST1; STAT4; ZNF500; ELK3; EMX2; SUB1; SPEN; MSX1; MLXIP; PBXIP1; BATF3; CEBPB; TRIM22; SOX10; IRF4; TCF12; VPS72; SALL1; PRRX1; NR0B1; SOHLH2; TXNIP; TOX; HLF; RUNX3; WWTR1; STAT1; ESR1; GATA6; IKBKAP; WT1
Down-regulation 76 ING3; PSMC3IP; KLF6; CREB3L1; BCLAF1; CCNH; NFATC1; RBM39; TSC22D3; ZZZ3; BRCA1; CREB1; EDF1; CITED2; WWC1; KLF4; FOXC1; MEF2A; CEBPG; ZBTB18; GATAD2A; BRD7; TFAM; TAF1D; ID1; ZSCAN31; E2F8; KLF2; BASP1; TDRD3; SIM2; MTF2; ID3; TOX3; BRD2; TBL1XR1; RYBP; YWHAB; ZNF423; TOB1; HIPK1; POU5F1B; NR4A2; ID2; SCAND1; BBX; CBFA2T3; FUBP1; TBL1X; FOSB; FOS; NFATC3; NFATC4; ERG; ZSCAN18; ZNF331; ZNF93; IRX5; ETS2; PEG3; MAF; ID4; AEBP1; ATF3; KLF3; CTBP2; ZNF160; SOX9; THAP11; ASCL1; TBX3; CEBPA; BTG1; ZFPM2; MYB; HOXC6