Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09495 Roscovitine GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 26 HDAC6; TBX2; SSBP2; ARID4B; JARID2; EGR3; HDAC7; BATF3; CBX6; HMGB1; SIX1; SMAD7; MEIS1; ZBTB38; FLNA; TSC22D4; MSX1; BCL3; HOXC10; ENO1; ARID5B; KDM5D; NR2F2; HLTF; IKBKAP; NFATC3
Down-regulation 78 UBE2I; TRIM29; NKX2-1; STAT1; IRF9; NFE2L3; ZNF423; ZNF33B; SNAI2; CEBPD; MXD1; TULP4; NR3C2; REL; HOXA1; ZNF273; PITX2; KLF3; MAFB; TAL1; NCOA2; ARL2BP; IRF6; FOXE1; PRRX1; KLF4; TCEA1; EN1; LYL1; ZSCAN18; TSC22D1; SOX10; LIN28A; ZNF91; ZNF165; HIRA; GATA6; JAK2; FOS; CERS6; IRX5; ZNF573; TFAP2C; TOX3; TCF4; MYCL; HOXD1; KLF2; TRPS1; TFEC; SATB1; MYB; ZBED2; INSR; ZNF721; ZBTB18; TCF7L2; BCL11A; CTBP2; E2F5; IRF8; NANOG; FOXG1; ZFPM2; ID4; SPIB; TBX3; LEF1; IKZF1; AEBP1; SPDEF; ESR1; TLE4; PBX3; MEF2C; ERBB4; PPARG; ZNF586