Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09494 Roscovitine GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 43 TCFL5; STAT5B; HDAC6; E2F6; JUNB; EYA2; RHOA; TRIM16; BHLHE40; SUB1; ZMIZ2; SMAD7; ID2; ASH2L; ZKSCAN1; STAT5A; CITED1; MKL2; EZH2; JUP; ZNF107; COPS2; FOXD1; POU2AF1; BCL3; SLC2A4RG; IRF4; BATF3; ELF3; PDLIM1; JUND; SOX9; RXRA; ZNF146; HHEX; HLF; SMAD1; FLNA; TRIP6; TBX3; CREB1; SMARCA1; IKBKAP
Down-regulation 111 CHD8; ETV1; AHR; NR4A1; SPI1; GATAD2A; PSMC3IP; ELF4; SP100; CCNH; ZNF721; ARNT2; MYCN; ETS1; MAF; APEX1; ZFPM2; PQBP1; HMGB3; DACH1; PHIP; ZBTB20; ZNF160; HOXB5; INSM1; ZNF33B; NR2C1; UBE3A; NR4A2; MED23; FOS; HMBOX1; ZNF93; ZEB1; TFDP1; ARL2BP; SALL2; NHLH2; TSC22D1; PRDM10; UBE2B; RNF138; JUN; ZNF611; CHD7; ZNF573; NEUROD1; TOX3; ZKSCAN7; FOSB; TAF1D; ZNF224; ZNF329; PAWR; MXD1; NR2F6; TDP2; MLLT10; NFATC3; ZNF654; BRD7; TGFB1; IRF9; KLF6; ZNF711; MED14; ZSCAN18; IRX5; CITED2; HOXD1; LEF1; TLE4; ASCL1; ZNF587; CREM; HIPK1; NKX2-2; THAP11; CBFA2T3; WT1; CTBP2; IRF8; ZNF83; TCF21; NPAS2; RUNX3; EYA1; ZBTB18; SPIB; FOXF1; PBX3; ZNF665; ZNF165; MNDA; ZFP36L1; HEY1; EHF; FUBP1; ZNF544; ZNF331; ERG; ZIC3; ATF3; AEBP1; TOX; MYBL1; SPDEF; HES1; PEG3; SSBP2; ZNF586