Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09493 Roscovitine GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 17 NR3C1; ELK3; MAX; KLF10; RNF6; MEOX1; HLTF; BMI1; PURA; FLNA; ETV5; NCOA4; TAF10; HMGN3; RFX5; ID1; NR2F2
Down-regulation 115 PUF60; HSF1; NFE2L3; NFATC1; FOXA2; ZNF219; ZNF34; PAWR; SOX12; HNF4G; LMCD1; SSBP3; FOXG1; MYCL; PGR; ZNF623; KDM5D; ZNF835; THRB; ZNF7; ATOH1; ZNF350; AR; DLX5; NFATC3; LHX3; MNDA; EHF; NR3C2; RUNX3; DLX2; ILF2; FEZF2; CRYM; ZFY; AGO2; SALL2; HEY2; MXD1; NR5A2; INSM1; ZNF394; SNAI2; SPIB; KLF4; ZIC3; THRA; PLAGL1; BARX1; CREB3L1; IRF6; CBFA2T3; SPDEF; BCL11A; ZNF264; SOX2; OVOL2; EMX2; ELF3; TCF21; HDAC5; PRDM14; ZNF682; ZNF667; TCF7L1; THAP11; YBX3; HIPK2; ARNT2; PIR; HEY1; OSR2; ZNF273; ZSCAN18; CTBP2; ZNF44; ZBTB16; BNC2; KLF3; ZNF573; ZNF711; ERBB4; EN1; OLIG2; ZNF117; ZNF589; AEBP1; TLE4; HOXB2; TCF4; SIX3; PBX3; ZNF551; MYB; NR1H2; ZNF165; ZNF467; TRIB3; MAF; KLF9; E2F5; SATB1; TFEC; ATF3; NANOG; WT1; ZNF665; HIC2; LIN28A; PPARG; MEF2C; TFAP2C; DACH1; ZNF586; SSBP2