Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09492 Roscovitine GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 18 ZMIZ2; RERE; SOX9; SPEN; SMARCD3; SATB1; BATF3; NCOA4; BRD8; PCGF2; ETV5; ELK3; TRIM28; BCL3; SMAD2; RFX5; ARID5B; IKBKAP
Down-regulation 88 HMG20B; NFE2; MXD1; PHIP; ID1; CEBPG; TDRD3; ATF3; HIC2; SNAI2; ZNF721; KLF4; URI1; ZEB1; LIN28A; TAL1; ZNF573; ZNF91; HHEX; MYCN; NR3C2; TFDP2; ARNT2; FOXF2; MAF; REL; AEBP1; ZBTB20; ZNF652; ZNF44; HMGB3; ID4; ZNF165; ZNF273; EMX2; ZIC3; ZNF254; ZSCAN31; ZNF711; EN1; NFATC4; ERBB4; HOXD1; ID3; ZNF160; ZNF665; ZNF611; ZNF423; KLF3; TOX3; ZNF682; HEY2; HOXB2; JUP; CBFA2T3; MNDA; INSM1; TOB1; TFEC; TCF7L2; SALL2; JUNB; MECOM; NANOG; MYB; KLF9; TCF21; HEY1; FUBP1; TLE4; IRF6; ZNF415; HIRA; ST18; SAP30; ZNF117; NEUROD1; ESR1; WT1; ZFPM2; HES1; NR4A2; TCF4; ZNF586; DACH1; SSBP2; PPARG; MEF2C