Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09491 Roscovitine GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 26 NFKB2; TCF25; HOXA10; ERCC3; SMARCA4; ZZZ3; THAP10; RFX5; ZNF12; RERE; TRIM28; AFF1; SIX1; ETV5; BMI1; EYA2; BRD8; NCOA4; CRY1; ELK3; HDAC9; STAT1; NR2F2; BHLHE41; THAP11; IKBKAP
Down-regulation 85 EGR1; MTA1; BHLHE40; XBP1; NFKBIA; CTNNB1; TSC22D3; KLF7; KLF9; CREB3L1; NFIL3; FOXF1; MAFF; LMCD1; PAX6; IRF7; VPS72; FOXA2; IRF1; SSX1; ZIC3; STAT3; NCOA2; PDLIM1; ZNF253; TCF4; REL; SNAI2; JUP; BACH1; ZIC1; CALR; SATB1; KLF6; MYCL; EN1; ATF3; SOX21; TGIF1; ZNF665; TLE4; ZNF165; ATF4; POU2AF1; PITX1; NR2F1; PRRX1; TFEC; BTG1; MAF; ZNF117; FOXO1; NKX2-2; ZNF273; E2F5; AEBP1; ZNF573; ZNF711; ID4; CREM; PAX5; HES1; ZNF91; IRF6; TRIB3; NFATC4; LIN28A; GATA6; ZSCAN18; HIC2; KLF3; MAFB; TRPS1; TXNIP; CBFA2T3; INSM1; ZFPM2; ZNF586; LEF1; TOX; NEUROD1; SSBP2; MYB; TOX3; ERBB4