Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09489 Torin-2 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 245 HDAC6; KLF13; SETDB1; PAXBP1; GON4L; SUPT7L; ZNF211; NR2C1; E4F1; FOXN3; ZNF692; DDIT3; NR1H3; CALCOCO1; EZH1; DBP; ZNF3; ZKSCAN1; MYBL1; GTF2F1; ZNF268; TSC22D3; HMG20B; HBP1; ZNF266; ZNF79; ZNF45; FOXO4; SIRT7; FOXO1; ZNF133; MZF1; PIAS4; ZNF408; CDK7; RXRB; TP63; ZNF91; HOXB5; ZNF444; TBX21; CXXC1; MAFF; TCEA2; MED12; HINFP; UBE2B; TRIM29; RING1; TAF6L; ZNF24; USP21; ZNF76; SNAPC4; ZNF263; IRF7; EZH2; ZBTB48; PSPC1; THAP3; HDAC5; GATA1; EHMT2; ZNF419; KLF1; BATF; APEX1; ING4; GCFC2; ARID4B; NFIC; SUPT6H; PCGF1; KLF5; ZNF551; ZNF292; ZNF219; ZNF83; CHD1; ZIC1; CEBPB; ZNF562; ZNF33B; PSMC3IP; CAMTA2; RXRA; ZNF177; ZNF500; ATF4; BTAF1; TWIST1; SP2; FOXF2; MYRF; EP300; ZNF227; IRF3; TDRD3; DLX4; ZXDC; PPARD; SMAD6; PPARG; ZNF44; AFF2; PPP1R13L; RLF; PSMD9; ZNF7; ZBTB16; ZNF134; STAT2; PHIP; COPS5; TAF1; REPIN1; TAF1C; ZNF131; ZNF239; HOXB7; KAT7; ZNF224; TRIM22; SUPT3H; SIX3; ZNF12; SAP18; NRL; OSR2; MYCL; ZNF32; ZBED1; SIX6; ZBTB7A; HOXB6; LPIN2; ZSCAN9; TLE2; NFX1; PRKDC; ZNF654; POLR3C; PLAG1; CIR1; SSBP3; ATN1; CERS4; ZNF195; MBD4; ZKSCAN4; ZNF202; ZNF506; RARG; ZNF337; MXI1; FOXA2; ZNF215; FOXL2; ZNF304; TBL1X; CIZ1; IRF9; KDM5D; KLF11; LHX3; HMGB3; SPDEF; BACH2; TRPS1; CBX7; ZNF778; CBFA2T3; ZNF586; ZNF688; STAT4; TRIP6; ID2; HOXB2; TGIF1; BTG1; IKZF1; ZNF264; ZNF235; TAL1; ZNF667; TFDP2; ZNF273; TBX3; ZNF426; ZNF587; ZNF394; SOX4; VPS72; ZKSCAN7; SCAI; EN1; TBX1; ZIC3; THRB; TCF7L2; GFI1; MDM2; EYA2; NR5A2; MYF6; ZNF467; L3MBTL1; TCF7; ZNF544; MED14; ZNF117; JUP; IRF6; KLF6; MNDA; KLF3; ZNF711; ZNF217; ZNF611; ZNF573; BRD8; SOX13; ZNF669; RORA; YBX3; ST18; KAT2B; SPIB; ZFPM2; ZNF665; ZNF160; ZBED2; FOXD1; ZNF43; NANOG; HOXD1; EGR2; ERBB4; ID4; ZNF589; HEY1; BHLHE41; THAP11; TXNIP; IKBKAP
Down-regulation 85 MYCBP; NFKBIA; XBP1; SMARCA4; CBFB; PAX8; SFPQ; WWC1; TBPL1; CREB3L2; DNAJC1; TSC22D2; YAP1; PARP1; TFDP1; FOXO3; MEIS1; C1QBP; WWTR1; HNRNPD; BIRC2; SMARCA5; ISL1; TMF1; HOXA10; NRIP1; MYBL2; NUP62; BMI1; ZBTB38; POLR2A; ELK3; BCLAF1; ENO1; PURA; HSBP1; PHOX2B; CTBP1; HDGF; CREB5; CARHSP1; HMGB1; CLOCK; ELF1; SUB1; ZBTB1; YWHAB; ETS2; MTDH; HOXC10; RYBP; AFF1; TCF4; MAZ; ZNF512B; SMARCA1; HIPK3; CBX3; FOXJ3; BHLHE40; STAT3; SALL1; HAND1; JUND; YBX1; CREB1; MAGED1; DNMT3B; TGFB1; RBPMS; ERG; CRYM; CSDE1; TBL1XR1; RFX5; SATB2; MAF; HMGN3; HLTF; NKX2-2; SOX11; FLNA; DACH1; ESR1; NR3C1