Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09488 Torin-2 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 361 HDAC6; HBP1; DDIT3; GCFC2; ZNF133; ZBTB16; SETDB1; SIRT7; GON4L; PMS1; TSC22D3; PAXBP1; CRTC1; NR2C1; SRCAP; PSPC1; ZNF268; E4F1; SOX2; ZNF473; ZSCAN32; ZNF45; ZNF444; E2F4; ZFHX2; TFAP4; TDP2; TAF6L; CBFA2T2; ZNF562; CEBPD; PIAS4; MZF1; ZNF239; TRPS1; ETV7; ZNF500; SP140L; ZNF276; TRIP11; ZNF195; NAB2; POLR3C; ZIC1; MED15; ETV6; ZSCAN9; ZNF224; FOXF2; TCF25; DNMT1; FOXG1; ELK4; ZNF223; CEBPB; EZH1; SP110; CIC; MYNN; LZTR1; STAT4; SIRT2; TCEA2; TCF3; ZNF222; PROP1; CEBPE; ZNF232; ZNF140; ZNF74; RING1; SUPT7L; CAPN15; ZNF35; HDAC11; ZNF91; ZNF33B; CAMTA2; MLXIPL; LHX3; ZNF205; TRIM33; SOX13; PCGF1; ALX3; CALCOCO1; ZNF75D; ZNF606; GBX1; MXI1; ING4; HDAC9; ZNF227; HOXC4; MNT; ZNF266; LHX2; SOX10; HMX1; IRF9; ZNF573; NHLH1; ZKSCAN3; ZNF211; THAP10; ZNF771; SNAPC4; NR2E1; ZNF112; ZNF24; MAP3K10; MED12; HEYL; KLF11; HINFP; TAF1C; ZNF816; ZNF623; CBX4; NEUROD2; CNOT2; ZNF219; PRDM2; PHF1; ZNF557; SIX6; ZNF22; PBXIP1; ZNF574; ZNF8; FOXJ1; ZNF671; NR5A1; EHMT2; RORA; HOXC11; BRWD1; SSBP3; TBX21; FOXA2; ZKSCAN1; BARX1; OVOL2; ZNF544; SPDEF; FOXO4; TFAP2A; NR2F1; ZNF235; PPP1R13L; POU3F2; AIRE; CEBPA; ZNF324B; ZXDC; ZNF93; TRIB3; HDAC4; ZNF180; HOXB1; HOXA3; MYOG; HOXD1; IRF3; PRDM14; TBX19; ZNF778; ZKSCAN4; ZNF701; HSF4; ETV2; ZNF688; CERS4; ZNF667; ZNF250; FOXN1; TERF2; NRL; NR1H2; ARNT2; HOXB2; TEAD3; EN1; ZNF787; THRB; ZNF419; HIF3A; ZNF131; PPARD; IFNB1; ZNF264; DBP; SCRT1; NR1H4; ZBTB20; ZNF350; SPIB; KDM5C; NEUROD6; KDM4C; ARID5A; KLF15; VPS72; GATA1; ZNF432; ZNF304; KLF9; ETV1; ARNTL; ZBTB48; FEZF2; ZNF354A; SALL2; CNOT3; TGIF1; ZBTB7A; NFATC4; TAF1; ZNF32; TULP2; SKIL; GLI1; BCL6; PHIP; BANP; MAFF; MAML3; CHD2; HOXB5; RSF1; KDM5D; TP73; TULP3; KLF13; NFIX; TBX1; ZNF154; AR; SUPT3H; PNRC1; GTF2IRD1; DMTF1; ZNF692; NR1I3; RCOR3; HDAC5; GLI3; WNT4; CREBL2; NFX1; ZNF44; SPI1; TULP1; IRF6; ZNF551; ZNF202; ZNF430; NR2F6; ZNF225; ZNF507; TP63; NR0B2; ZNF175; TLX3; VENTX; SOX5; ZNF43; ZNF7; JUP; ZNF132; ZNF362; TWIST1; ZNF34; ETV3; SOX9; SOX3; NKX2-2; CDIP1; NR1H3; ST18; MYBL1; TCFL5; ZNF345; ZNF324; CBX7; GTF3A; SOX21; ZKSCAN8; ZNF669; ZNF10; L3MBTL1; ZNF83; POU6F2; SHOX2; PRDM10; PAX6; ATOH1; PRRX1; KLF3; ZNF85; ZNF695; OLIG2; FOXO1; CUX2; ZNF117; ZNF587; ZNF331; HLF; IRF7; SRY; GFI1; SIX3; SOX18; TRIM22; ZFP36L1; MYRF; ZNF415; EYA2; ETV5; ERBB4; DLX5; HOXD3; IKZF1; ATF4; HIRA; IRF8; HES1; SOX17; ZNF273; NEUROD1; ZNF665; ZNF586; ZNF141; IFI16; BNC2; ZNF257; ZHX2; SOHLH2; ZNF711; ID4; ZIC3; ZNF611; MED14; BCL11A; TCF7; MAFB; ZSCAN18; BNC1; NANOG; AEBP1; BRD4; KAT2B; PBX1; BHLHE41; STAT1; ESR1; ZNF589; CBFA2T3; ZFPM2; THAP11; PEG3
Down-regulation 118 NFKBIA; MYCBP; ATF1; GTF2A2; PAX8; SMARCA5; MTDH; BASP1; TSC22D2; EGR1; CCNA2; SFPQ; PARP1; NRIP1; SMARCE1; MED6; TP53; NFE2L1; FHL2; PIAS2; DRAP1; CCNE1; REST; NUP62; ECD; RHOA; TBPL1; EDF1; ENO1; BMI1; SMARCA4; HNRNPD; USP22; BCLAF1; CTR9; RBBP4; RCOR1; CREG1; ADNP2; YBX1; YWHAB; TBL1XR1; BIRC2; ENY2; ETS2; SUB1; KLF6; PTRF; MYBL2; HOXA10; DNMT3B; MAGED1; NEDD8; MBD2; RBPMS; DAXX; HDAC1; CREB3L1; ELK3; FOXJ3; NRBF2; BHLHE40; RBM14; CBFB; MYCN; HOXC6; KLF10; ZBTB1; NR2F2; DPF2; ELF1; MEF2A; HIPK3; HMGB2; NFYC; MNAT1; SP3; SMAD2; BBX; CREB3L2; AFF1; PSMC3; TCEB2; SAP30; MEIS1; CBX3; CTNNB1; ZBTB38; NCOA4; RNF10; RYBP; CCNC; CRY1; TRIM32; PUF60; ZEB2; ZNF146; CREBZF; JARID2; HSBP1; LMCD1; IRX5; RFX5; EGR2; ZBTB18; HLTF; NKX3-1; NCOA1; MED1; CEBPZ; TLE4; LEF1; MSX1; MNDA; TOX3; FLNA; PPARG; NR3C1