Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09487 Pelitinib GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 89 POU4F1; MGA; NPM1; TGFB1I1; CNBP; E2F3; GCFC2; ZNF350; CREG1; RNF141; TRIM22; EGR4; PFDN5; ZFX; TMF1; SALL1; LPIN2; ZBTB6; LEF1; ZNF813; ZNF623; ZNF529; TCF3; CREB3; TWIST1; MSX1; NKX2-1; NKX2-2; SMARCA1; CNOT3; RSF1; SF1; MECP2; GATA2; HOXD11; COPS5; EGR2; NCOA4; DEK; SMARCD3; POU4F2; HOXB7; NR1I2; FOXJ3; SAP18; FOXM1; CARF; KAT6A; HMGB2; ZNF532; ID3; ZNF22; SMARCA2; HOXB6; NR3C2; HMGB3; FOXO1; ST18; NFAT5; MAFF; CBFB; ZFHX4; L3MBTL1; VDR; ZFP36L1; TCEA1; TRIP6; PRRX1; BRD2; ISL1; SOX17; SOX11; TAF10; IFI16; CUX2; NR1D2; HOXD1; EYA1; HIC2; CHD7; PEG3; AEBP1; RUNX1; SAP30; ERBB4; ARNT2; NFATC3; MEIS2; ESR1
Down-regulation 59 KLF5; ZMYND8; ARNTL; SIRT7; LDB1; CHD8; TSC22D1; KLF6; SUZ12; RYBP; DNMT3B; RBPJ; FOSB; CREB5; PTRF; ETV4; SCAND1; SIAH2; FOXC1; CRYM; MED21; UBP1; ZNF652; ARID5A; BCL6; PIAS3; TP63; BCL11A; MLXIP; MEIS1; KLF4; RFX5; CREB1; ZNF266; STAT1; MBD2; RUNX3; SOX10; KLF10; CRY1; BMI1; INSM1; BNC2; CARHSP1; JAK2; ZNF611; ZFP36L2; ZNF721; FOS; LMCD1; BAZ2B; THAP11; CTBP2; HOXC6; LITAF; IKZF1; IRF8; NR3C1; PPARG