Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09485 Pelitinib GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 53 CEBPZ; CEBPG; PCGF1; ATF4; SCMH1; SREBF1; CDYL; CBX6; MNAT1; TRIB3; TCEA1; THAP10; TBPL1; CBX7; BCL11A; CREB5; EMX2; HIRA; FOXM1; NFIC; SPEN; ARNT2; CREBL2; OVOL2; FOXA1; ELF4; PAWR; SUPT3H; NR1H2; SOX2; TOX; TDP2; TWIST1; ZMYND8; BNC2; MYRF; SPDEF; IRF6; FOXG1; PAX5; HOXD1; INSR; CBFA2T3; ST18; KLF4; KLF11; POU2AF1; LITAF; INSM1; CTBP2; SPIB; TOX3; TLE4
Down-regulation 51 HOXA5; NRIP1; SMAD3; BHLHE40; EGR1; ZKSCAN1; KLF10; RCOR1; STAT3; SMARCE1; SFPQ; MAGED1; TFDP1; PDLIM1; EGR3; ZNF813; HMGA2; RFX5; ID4; MEOX1; NPAT; SMAD7; ID3; ERBB2; RARA; ZNF516; ZNF217; MXI1; PKNOX2; BBX; SATB1; MED1; MYCN; ZIC1; EGR2; CREB1; TXNIP; TAF10; ZNF423; MYBL1; BTG1; ELK3; NFATC3; ENO1; SOHLH2; FLI1; LEF1; PEG3; WT1; NR3C1; PPARG