Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09477 Azd-6482 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 30 HDAC6; SIX1; FOXO4; PPARG; PBRM1; KLF10; NR2F1; TRIM29; TBL1X; PIR; FLNA; SOX4; ID2; VEZF1; TAF10; TSC22D2; ELK3; WWTR1; KLF5; SMAD2; ARID5B; BMI1; MECOM; SMARCA1; CREB1; TOB1; ZBTB38; NR1D2; MSX1; NFATC3
Down-regulation 99 CBFA2T3; PGR; SIAH2; GATA4; ZNF764; MYCN; ZNF33B; TDP2; HEY2; SOX2; ZNF426; DLX2; ZNF107; RBPMS; LIN28A; ID4; SPIB; ZBED2; SALL1; FOXE1; ZKSCAN7; LEF1; HIRA; HESX1; ARNT2; GATA6; ESR1; HOXA1; SOX17; ZSCAN18; BCL11A; JUN; TFAP2C; ZHX2; HOXB2; PBXIP1; MAF; DLX5; ZNF652; IRF6; OLIG2; ZNF165; TRIB3; TAF1A; BRD7; SOX3; BACH2; E2F5; ZIC3; JAK2; ZNF710; ZNF516; GRHL2; FOXO1; ZFP36L2; E2F8; NR1H4; TFDP2; ZNF273; ZNF141; EMX2; ZNF532; EN1; ZNF721; POU2AF1; HIC2; ZNF611; ZNF124; AEBP1; TSC22D1; MYRF; TFEC; ZNF257; ZNF682; BNC2; TRPS1; MYB; NANOG; ZNF665; WT1; PAX5; ZNF264; BNC1; HDAC9; SOX13; SPDEF; ZNF467; THAP11; ZNF117; MNDA; CEBPA; PBX1; MEF2C; ZNF589; TLE4; NEUROD1; TCF4; SSBP2; ZNF586