Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09474 Tgx-221 GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 322 TERF2; IKZF1; SETDB1; MYRF; LHX2; GATA1; HIRA; PROP1; ZHX2; TCFL5; ATN1; TAF12; NR1H2; ESRRA; TGIF2; ZNF654; NCOA2; NFIX; FOXI1; DNMT1; ZBTB16; MAML1; SIRT2; HINFP; USP21; ZIC1; BACH2; SSBP3; FOXF2; SMAD1; INSR; TCF3; HIPK2; MXI1; ZNF557; GLI2; TAF6L; PKNOX2; TAF1; ZNF75D; HSF1; ADRB2; CALCOCO1; MED12; NEUROG1; TP73; SOX18; TRIB3; JAK2; NEUROD2; SOX5; HOXB13; ZNF423; CBFA2T3; SSX3; ZNF688; PEX2; PRDM2; SOX2; TCEA2; ZKSCAN1; BANP; SPDEF; AEBP1; TULP3; ZNF131; POLR3C; HOXA11; ZNF276; GBX1; VPS72; MED27; CAPN15; VENTX; TFAP4; ZNF34; BCL11A; CDYL; SOX11; BARX1; LHX3; TBX1; ERBB4; TEAD4; NKX3-2; NRL; ZNF589; ZKSCAN3; PRDM14; PDX1; IFNB1; SMARCB1; MKL2; SMARCD3; TAF6; AIRE; SUPT3H; ZNF74; KDM4C; THRB; MEIS2; NFIC; FOXN1; VAX2; CBX2; ZNF91; PIAS4; RBPJ; NR4A2; HBP1; TFDP3; NHLH1; LHX1; ZNF500; PRRX1; FEZF2; KLF1; ZNF467; GLI3; TEAD3; ST18; ZNF771; AFF2; RARG; MYBL1; SALL2; SOX3; SCRT1; NR2F6; SSX7; TCF7L1; EGR2; ZIC3; ZBTB7A; NR3C2; ING4; MYOG; REL; ELF4; ZNF33B; HOXD13; TCF4; KLF15; CDX2; ZFPM2; ZKSCAN4; EZH1; COPS5; GRIP1; ETV2; PBX1; SRY; CDK8; ARID3A; ESRRG; HOXB8; TULP2; CERS4; THRA; SOX13; NFATC4; TBX5; CBL; CEBPD; MECP2; ZNF710; ZNF232; TLX3; ASH1L; BTG1; CHD2; FOXN3; PRDM10; NEUROG2; E2F5; JUP; ZNF692; ZNF117; NANOG; IRF7; LYL1; EMX1; CREM; PBX3; UBE2B; ZBTB3; PPARD; POU6F2; ATF5; EPAS1; ZNF778; MEOX1; HOXA1; SP4; EN2; TAF5L; ZNF343; NR6A1; RAD21; HOXB2; AGO2; PLAG1; OVOL2; LIN28A; SOX21; ARID3B; HIC2; KLF3; IKZF2; ZNF669; MDM4; ZNF132; NLK; ARL2BP; ZNF623; NR4A3; ATF3; ZNF507; IFI16; ZFP2; MED20; JUN; FOXH1; BRD4; KLF11; NKX2-1; ZNF202; CBX4; SOHLH2; TBR1; MEF2C; IRF4; ZSCAN31; MYCL; ZNF154; TCEA1; PEG3; FOXE3; HOXD1; MYB; ZNF665; ZNF32; DCC; TFAP2A; TRPS1; ZNF224; GFI1; PROX1; SOX17; FOXE1; BHLHE41; RBL2; ZBED2; ZNF235; ZNF257; CUX2; TCF21; PNRC1; IRF6; VDR; TWIST1; ZNF652; FOXO1; NHLH2; ZNF214; POU2AF1; ZNF141; L3MBTL1; ZNF362; ZFP69B; TOX3; ZNF273; ZNF124; KAT2B; LEF1; ZNF695; ZFP36L1; HMGB2; BNC1; HLX; CRYM; ZNF93; OLIG2; SIX3; HMGB3; NR2F1; CHD7; ARNT2; SOX9; SNAI2; FUBP1; CTBP2; FLI1; ZBTB18; HEY2; HDAC5; BNC2; ZNF44; ZNF573; ZFP36L2; SPIB; TXNIP; SSX1; SATB1; NEUROD1; KLF9; THAP11; ZNF165; IRF8; LITAF; WT1; MDM2; PAX6; FOXF1; TOX; EYA1; ID3; ARID5B; CEBPA; DACH1; TFAP2C; TLE4
Down-regulation 96 XBP1; SUB1; BCLAF1; NFKBIA; DRAP1; C1D; KLF10; IKBKAP; SFPQ; BMI1; ZBTB38; ADNP2; HSF2; RNF10; REST; RCOR1; UBP1; SMAD3; FOXC1; NAB1; TP53; ZNF468; TSC22D2; ZNF432; USF2; TBP; SCAND1; BAZ2A; HLTF; SNW1; ZMYM2; AFF1; CBFB; ZNF134; EDF1; TBL1XR1; SMAD2; KLF12; BASP1; RUVBL2; BAZ1B; TSC22D1; FLNA; COPS2; RBM14; ZNF14; ACTL6A; ELF5; USP22; KAT7; PAX8; ERBB2; HOXC6; RERE; FOSL1; TRIM28; TRIM32; HMG20B; ENO1; FOXJ3; NEDD8; C1QBP; HOXC10; DNMT3B; NFIB; MED1; HNRNPD; WWTR1; ZNF146; ZNF302; KLF6; HMGN3; CRY1; MEIS1; CARHSP1; HMGA2; SP2; ZNF586; NR1D2; ZNF587; ZNF329; ZBTB20; HTATIP2; FOXD1; TRIP6; FOSB; SMARCA1; RUNX3; ELK3; MSX1; HOXB7; ZNF551; PIR; INSM1; ELF3; ID1