Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09473 Tgx-221 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 377 SRCAP; NEUROG1; HBP1; RBFOX2; ALX3; LZTR1; PPARD; FEZF2; LHX6; CEBPZ; NR2F1; THRAP3; PITX3; VDR; CNOT3; TFAP4; LHX3; NEUROD6; SNAPC4; MED25; ASH1L; PRDM2; ZFHX2; RORC; ZNF692; MAP3K10; ZNF444; GATA1; PAX5; LHX2; ZBTB16; MEF2C; MAK; PCGF1; CBX4; NEUROD2; NR5A1; SOX2; RRN3; SPI1; ZNF557; TFEB; TCFL5; MEF2D; NKX2-1; HOXB1; SMARCB1; RREB1; BACH2; FOXO1; TAF1; APBB1; KLF15; ZNF232; IKZF4; SP100; HOXB2; CRX; SATB2; PBX1; NR2E1; ZNF133; HOXC11; HNF4A; AFF2; PROP1; GBX1; EMX1; TAF6L; AR; HLX; PITX1; TGIF2; CBX8; RARA; HMX1; ZBTB44; MEIS2; MKL2; ZKSCAN3; ZNF500; SOX12; ZNF771; L3MBTL1; LYL1; VENTX; NR1H2; TEAD3; NRL; MAML3; IFNB1; PEG3; STAT5B; MYOG; POU5F1B; CEBPD; NLK; SCAI; AIRE; PRDM14; THRB; NPAS1; ZNF224; TRPS1; SPDEF; PRDM12; ZNF75D; PGR; ZNF512B; TBR1; HOXA3; ZBTB43; ERBB4; ZNF623; NHLH2; SRY; ONECUT1; RORB; NFATC4; TEF; FOXA1; CERS4; NHLH1; FOXI1; ACTL6B; IRF8; ZBED1; TERF2; ZNF345; GBX2; TAF4B; PAXBP1; JUP; KDM5C; PKNOX2; PAX6; ZNF239; RING1; TCF4; CHD2; CDC5L; TRIB3; ZNF688; NR6A1; TBX10; FOXH1; CAPN15; PDX1; ASCL3; WNT4; RBM39; RSF1; BRWD1; FOXN1; ING4; ATOH1; KAT2A; HIPK2; NEUROD4; HMGB3; CIR1; PBX2; HHEX; PRDM10; HINFP; TP73; ZNF701; FOXF2; ZFP37; PRDM9; HDAC5; ZBED2; TGFB1I1; YBX2; IRF7; KLF11; CALR; TFAP2C; ZNF354A; UTF1; ATF7; ZNF221; SCRT1; KLF8; TAF1C; TBX5; WHSC1L1; CBX2; SOX5; SALL2; ATN1; VAX2; PAX1; POU4F3; HOXB8; GRIP1; NR1I3; CSDC2; TULP1; SMAD9; CIITA; ZHX2; ZFP36L2; ETV1; BRCA2; ZNF235; ZNF423; PLAG1; NCOA3; ZIM2; KAT8; SSBP3; FOXG1; PRDM1; GTF2I; SOX11; MBD4; ZNF589; ZNF214; ZNF835; TXNIP; KLF9; ZNF778; CBFA2T3; ZNF132; ZNF362; CDIP1; BCL11A; PNRC1; ZNF334; ETV3; SMARCD3; CHD9; ZNF507; ZIC3; ZNF343; POU6F2; ARNT2; ZNF124; NR2F6; CREB3L2; ZBTB48; ZNF177; ZNF550; PRDM5; ZNF711; FLI1; ZNF131; TLX3; FOXE3; ZNF154; BARX1; FOXL2; TTF2; MECP2; ZNF710; ZNF580; TAF5L; ZSCAN9; TULP2; STAT2; ZNF573; HLF; HOXD11; POU1F1; KDM5D; ZKSCAN8; ZNF223; SOX3; VPS72; HIC2; DCC; PAX9; ZNF391; MDM4; ZNF286A; NEUROG2; EZH1; HEY2; ZNF415; RFX3; TFDP3; ZNF471; SPIB; JUN; SOX21; OVOL2; CUX2; ZNF74; ZNF22; ZNF208; SSX7; ZNF324; ESRRG; ZNF331; ZNF467; PRRX1; TDP2; CARF; ZFY; THRA; CEBPB; ARID5B; VGLL1; POU2AF1; ZNF117; SUPT3H; ZNF141; ZNF654; CERS6; ZFP2; TFAP2A; ZNF202; ZBTB3; ZNF175; INSR; AEBP1; ZNF606; ZKSCAN4; NEUROD1; REL; ZNF695; ESR1; WT1; BCL6; RXRA; PBXIP1; SKI; HIPK1; NR3C2; SP4; PHF20; ZFP36L1; ZNF682; TRIM22; ZNF667; ZNF611; RORA; TCF7L1; LIN28A; HIRA; TCF7L2; MAFB; STAT4; ZNF257; OLIG2; TWIST1; ZNF665; EGR3; ZNF91; NANOG; BNC1; SSX1; E2F5; FOXF1; EHF; IFI16; PLAGL1; RBPJ; SALL1; SIX3; MYRF; IKZF1; BTG1; MNDA; EN1; NKX2-2; SOHLH2; KLF3; ZNF83; NR4A2; ZNF160; TOX3; LITAF; IRF6; TLE4; MYB
Down-regulation 101 NFE2L1; CCNE1; NFKBIA; DRAP1; HOXB7; HNRNPD; RNF14; HOXC6; FOXO3; HMGN3; HSF2; NKX3-1; SMARCA5; PIR; TRIM29; ETS2; EZH2; PIAS2; PCBD1; HMG20B; ZNF443; PAX8; KLF6; SMARCA4; NR2C1; BCL11B; AATF; NCOA4; PSMC3; REPIN1; CEBPG; ENO1; WWP1; TSC22D2; FOXO4; TRIP4; MYCN; JARID2; CRY1; ZMYM2; SP2; SMAD3; TSC22D1; KLF12; BMI1; NCOR2; ADNP2; BLM; DNMT3B; AFF1; YBX1; HDAC1; FOSL1; ALX1; XRCC6; ZNF281; FOXM1; ZNF134; NCOA6; CBX3; RNF10; MED1; RHOA; ELK3; RBPMS; SFPQ; ELF3; ZSCAN18; TAF10; DDX5; SMARCA2; TCF12; ZBTB38; ZNF146; HTATIP2; BIRC2; SOX4; BBX; TRIM28; SMAD2; MSX1; ZNF586; RAN; SMAD1; BHLHE41; YWHAB; RUNX3; ZNF329; PCGF2; HLTF; TBX3; HOXB6; MECOM; MAGED1; MEOX2; SAP30; NPAS2; FLNA; STAT1; ATF3; NR3C1