Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09472 Tgx-221 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 120 NFKB2; HES1; TSG101; COPS5; NCOA2; MYRF; SMARCB1; JUP; SOX10; ZNF217; CALCOCO1; IKZF1; KLF11; CHD8; HOXB2; HMGB3; MEOX1; UBE2B; RBBP8; TAF12; SP140; HMGB2; IRF7; MTF1; VDR; CEBPG; SIX2; TGIF2; MED17; KAT2B; HOXB6; NR4A1; PITX1; TRIM22; NR1H2; ATN1; STAT5B; PCGF3; TP63; SIM2; HOXB5; TFCP2; FUBP1; ZNF589; ZNF232; FOXI1; ZNF44; CIITA; SOX5; HOXC4; ZNF423; RARG; PRKDC; KDM5D; EGR3; PRDM10; EMX2; STAT4; ZNF281; STAT5A; SMARCD3; SIX3; EYA2; ERBB4; ATF3; BACH2; PLAG1; MYBL1; SOX3; PLAGL1; HIPK2; MAFF; INSR; MYF6; ZNF239; ZHX2; PRPF6; POU5F1B; MEF2C; TOX3; HIRA; PEG3; E2F5; ARNT2; PRRX1; PRDM2; PBX3; ZFP36L1; ZBTB18; ZNF710; ZFPM2; LIN28A; AEBP1; ZNF273; ZNF124; NANOG; ZNF331; ZBTB44; FOXO1; YBX3; MNDA; PAX5; SOX9; CHD7; HIC2; FOXF2; SPDEF; MDM2; IRX5; ZIC3; ESRRG; ZBED2; LITAF; NR4A2; MYB; IRF6; PBX1; ST18; ID3; ZNF586
Down-regulation 44 MEIS1; NR2F6; BASP1; RFXANK; DNMT3B; TSC22D1; RUNX3; HMGA2; HDGF; FOXC1; YBX1; BMI1; NAB1; BCLAF1; ISL1; TSC22D2; INSM1; ZBTB38; RNF10; RBPMS; WWTR1; BCL11B; TCEB2; SCAND1; SUB1; MAFB; ING2; NFIB; AFF1; MAF; THAP11; ETS2; ID1; NR2F2; HEY1; STAT1; CRY1; NKX2-2; ZNF146; BRD4; ENO1; CITED2; FOSB; NR3C1