Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09471 Tgx-221 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 100 IKZF1; TBX2; SMAD6; MEF2C; TSG101; HBP1; FOXO1; HMBOX1; DDIT3; PCGF3; GATA1; TAF12; PBX3; HHEX; FOXF2; LYL1; TRIB3; TWIST1; JUP; PAX5; NCOA2; RARA; NFIC; BPTF; EP300; LHX3; GATA2; CSDC2; INSR; EZH1; PRDM10; ZBED2; HIC2; CREB3L1; ARNT2; ZNF91; SMARCD3; ZNF165; SPEN; PLAG1; BACH2; HIPK2; IRF7; ZNF217; HMGB3; E2F5; PKNOX2; MYF6; MXI1; HOXB2; POU2AF1; CTBP2; ID2; MYRF; ERBB4; ZFPM2; RXRA; ATF4; OSR2; PLAGL1; AEBP1; MYBL1; ZNF467; PRDM2; HIRA; ZNF711; MEIS2; GFI1; KLF11; SERTAD2; FLI1; SPDEF; RORA; ZNF117; GATA6; LMCD1; SNAI2; FUBP1; CBFA2T3; SIX3; TCF7L2; NFATC4; CEBPB; SMAD1; E2F8; VPS72; ZNF141; ZNF232; SOX11; PBX1; BTG1; TXNIP; BCL11A; LIN28A; WT1; ZNF423; ZNF589; TCF4; KDM5D; ZBTB18
Down-regulation 49 UBP1; IRF1; C1QBP; SFPQ; ORC2; DNMT3B; MAZ; BMI1; FOSL2; NFYC; RFX5; HOXC6; ZBTB38; TRIM29; TSC22D1; BAZ1A; ELF3; AFF1; TGIF1; MBD2; YBX1; EDF1; STAT1; BIRC2; CREB1; FOSB; HNRNPD; SAP30; BATF3; TRIM28; DPF2; ZNF146; WWTR1; THAP11; FLNA; ELK3; HOXC10; FOXC1; MED1; NR4A2; JUNB; ENO1; HTATIP2; IFI16; TOB1; NR2F2; ESR1; NR3C1; PPARG