Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09470 Tgx-221 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 67 IKZF1; IRF7; TSG101; TRIM22; HBP1; IRF9; SP110; ZEB1; NCOA2; BPTF; ID4; LEF1; TCEA2; RING1; ZKSCAN1; SP100; SP2; RXRA; SALL2; FOXN3; FOXO1; IFI16; SUPT3H; TBX21; MYRF; HLF; TP63; AEBP1; HIPK1; FOXJ3; ZNF131; SAP18; AHR; HLX; SOX9; ETV5; ZNF22; TRIP6; OSR2; ZHX2; NFAT5; ZNF124; ZIC1; HIC2; HIRA; NR1H3; PEG3; SPDEF; HMGB2; TFAP2A; PAWR; EGR2; BACH2; KAT2B; ZFP36L1; HHEX; ZNF467; KLF9; ERBB4; ARID5B; HEY1; WWTR1; TRIB3; ZNF423; TXNIP; ZFPM2; MEIS2
Down-regulation 67 NFKBIA; FOSL1; CCNE1; YBX1; MAF; ZNF148; ETS1; EGR1; FOXC1; BCLAF1; HOXB13; HDAC9; AES; PA2G4; ZMYND8; YWHAB; C1QBP; SIX1; MEIS1; CENPF; ACTL6B; MAZ; BBX; UBP1; HDAC7; MYCN; PAX8; RERE; RFX5; TSC22D1; BRD2; POLR2A; SSBP3; NCOA6; SFPQ; HOXC6; RYBP; NR2F2; TSC22D2; SCAND1; DNMT3B; BMI1; NPAS2; HDAC1; HSBP1; THAP11; HOXB7; BHLHE41; FOSB; ISL1; YBX3; ZNF93; ZBTB38; ETS2; POU2AF1; NKX3-1; AFF1; INSM1; BCL11A; JUNB; DACH1; TCF4; GATA3; HTATIP2; SATB1; ID1; ESR1