Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09469 Azd-8330 GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 442 PARP1; GLI2; SIX2; USP21; HIVEP1; CBFA2T3; SETDB1; HMBOX1; MYT1L; SSBP3; EHMT2; BARX1; VAX2; ZNF556; SPEN; MYRF; IRF9; BACH2; ZFHX3; GATA1; HIRA; CHD8; FOXI1; JUP; CAPN15; NKX3-2; ZIC1; SOX11; LHX2; PITX1; NFATC1; JAK2; ZNF467; ZNF629; FOXB1; SIN3B; SUPT3H; SMARCB1; KLF11; AFF3; MTA2; ARHGAP35; PPARD; MDM4; SOX5; CAMTA1; TLX2; TFAP4; RARA; PRDM4; LHX1; SMAD4; KDM5A; SOX18; LDB1; PAX9; ST18; SALL1; TGFB1I1; NPAS1; IRF8; NKX6-1; IKZF4; TAF9; GRIP1; HR; TAF7L; ASH1L; ZBTB7C; SIX3; CIITA; TEAD3; SNAPC4; NR1I3; ETV2; GTF2IRD1; SSX1; KLF4; IFNB1; ZNF214; TP73; POLR3C; THRA; EMX1; PAX6; PITX3; MNAT1; SCRT1; ZNF771; TAF6L; SKIL; CUX2; ZNF257; GSC2; SOX13; KDM4C; YEATS4; GBX2; TCFL5; ZNF41; ING4; ZBTB48; BRDT; SOX14; GATA4; AFF2; ATOH1; TLX3; WNT4; HOXC4; SCMH1; ERBB4; HOXD10; PDX1; DAXX; HEY2; TCF7L1; TCF4; NR5A1; TEF; ZNF254; RORC; SHOX; HOXC11; TULP1; HDAC5; ZBTB16; BCL6; NCOA3; TAF5; ZNF75D; CHD2; ZNF814; ZNF780B; SOX3; NCOA2; TRIB3; REPIN1; MNX1; FOXD3; ZNF460; POU1F1; SMARCD3; FOXE1; TFDP2; SOX12; FOXA2; ASCL2; ZXDB; RING1; HOXB8; CD3D; SIAH2; HDGF; ZNF81; LBX1; ZBTB3; FEZF2; ARID4B; KLF1; HMGXB3; ZNF34; VDR; SRY; GRHL2; ZNF407; DMRT1; PAX4; TBX1; POU6F2; LZTR1; POU4F3; ZNF142; PGR; ZNF711; TULP2; ZNF345; ZNF688; KLF15; TGS1; ONECUT1; ZNF391; FOXG1; BNC1; PEG3; FOXN1; SRCAP; GCM2; RSF1; SPI1; TBX5; CRX; PRDM9; NOCT; CEBPD; TBR1; RXRA; GLI1; ZNF223; POU3F1; EBF2; RARG; POU2F3; GLI3; PEX14; ZNF362; VHL; NR5A2; NR1H2; HOXD13; MAML3; TBX4; VPS72; ZNF669; THRB; NR2F6; SMAD7; ZNF674; TFEB; NLK; RORB; ARID1A; CTNNB1; SKI; GCM1; STAT2; CBX4; CREM; SSX7; ZNF80; DCC; BRWD1; MYEF2; SUV39H2; NR2C2; ZKSCAN4; CBX2; SOX30; TTF1; ZNF492; HOXD12; CDIP1; VENTX; NEUROG2; MDM2; ZNF549; ZNF675; ZIM2; ASCL3; ZNF749; RBPJ; HSF4; ZNF423; ZNF202; ZNF682; PRDM2; TAF1; ZNF589; ETV3; ZHX2; LHX3; HCFC2; WHSC1L1; NFATC4; ZNF500; UTF1; PRRX2; ZNF471; SREBF1; FOXE3; ZKSCAN8; ZNF131; ZNF493; FOXF2; FOXN2; AES; POU3F4; NRL; OLIG2; ATF7; MSX2; STAT1; SIX6; OVOL2; ZNF710; MECP2; PBX1; ZNF234; TAF5L; TRIM22; PLAG1; ZNF613; ZNF132; ZNF157; SOHLH2; HIPK2; CRYM; SOX21; HAND1; SMAD9; EYA1; THAP9; IFI16; ZNF154; ZNF484; SMAD1; ZNF93; NFIX; FOXJ3; ESRRG; RNF2; ZFP37; RNF141; PKNOX2; ZFP2; HINFP; AR; TDRD3; IRX4; TBX19; BCL11A; IKZF3; FOXN3; ZNF155; MED20; ZNF571; SMAD6; HMGB2; ZKSCAN3; HLX; WT1; PRDM14; LZTS1; HDAC7; BACH1; PNRC1; NR3C2; NEUROD1; ZNF225; RFX3; MAK; ZNF442; IRF6; PAWR; COPS5; SP4; NEUROD6; TOX3; NR6A1; FOXA1; ZNF529; ZFHX4; ZNF695; POU2F1; SCAI; ZNF343; ZNF532; E2F8; ZNF778; ZNF208; KLF3; HEY1; FOXO1; PRDM10; IRF7; PITX2; MKL2; PRDM1; ZNF654; SALL2; TXNIP; TFDP3; SATB1; NR1H4; CIR1; ZNF177; ARNT2; ZNF286A; EPAS1; KLF9; ZNF334; REL; MYCN; LIN28A; TAF1A; STAT4; ZNF124; ZNF141; ZIC3; ZNF236; E2F5; PBXIP1; CREB3L1; TAL1; ZFP69B; ZNF117; TBL1X; HMGA2; ZNF329; HOXC10; NANOG; TRIM16; TCF7L2; JUND; MEIS2; GFI1; ZFP36L1; ZNF10; BNC2; PROX1; ZNF415; FOS; SOX2; MYCL; ZBTB44; ZNF165; ARID5B; SOX9; ZNF232; TLE4; HLF; SOX17; MYC; CHD7; MYBL1; INSR; NKX2-2; ZEB2; LEF1; MAFB; SPDEF; EN1; HIC2; AEBP1; MEF2C; FLI1; MECOM; TOX; ZFPM2; E2F2; GATA2; MYB
Down-regulation 118 HOXA5; FHL2; ZBTB38; RNF4; ZNF443; FOSL1; EGR1; NR1D2; TOB1; HSF2; SF1; ING3; DNMT3B; TAF7; C1QBP; ZMYM2; CBX3; ZNF468; ELF5; ZMIZ1; USP22; ZBTB11; ZNF419; SMAD3; TSC22D2; REST; SP100; HLTF; XRCC6; BCLAF1; ZBTB43; PIR; NR2F2; NAB1; BMI1; ZNF593; RNF14; FLNA; ZNF84; BRD8; CTR9; HNRNPD; ZNF302; COPS2; SCAND1; ZNF551; RAN; NRIP1; ORC2; SUZ12; PPARGC1A; SFPQ; SETD3; MEIS1; CBFB; NPAS2; BIRC2; ZNF134; ZNF587; NCOA4; PURA; MITF; ZNF12; HMGA1; SMARCC1; WWTR1; TRIM28; ENO1; STAT5B; ACTL6A; NR4A1; HOXA10; CITED2; AFF1; FOXC1; MED1; HSBP1; USF2; ZBTB20; ATF4; SUB1; ZNF146; NFYC; CTBP1; TGIF1; VEZF1; RFX5; ID1; RBPMS; TAF10; KLF2; BCL3; MED23; ZNF586; BAZ1A; HOXB7; HMGN3; ELK3; MAGED1; DDX5; ID2; BHLHE41; CITED1; NFE2L3; ELF3; ZNF83; ZNF264; YBX3; THAP11; TRIP6; ZNF160; TBX3; FOSB; MSX1; CREB1; HTATIP2; HOXC6; NFATC3