Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09467 Azd-8330 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 479 MYRF; SIAH2; ZKSCAN1; SUPT3H; PROP1; ETV1; TAF6L; RING1; E4F1; NR1H2; SETDB1; BARX1; LHX3; PPARD; HBP1; RELB; MXI1; ZNF771; TCEA2; CEBPD; PKNOX2; SOX2; ZNF276; MED12; HIRA; NCOA3; AFF2; ZNF557; ZNF692; MAP3K10; IRF9; TWIST1; KLF15; HSF4; HMBOX1; TERF2; MED25; TEAD3; RORC; ZNF654; SSBP3; NR2F6; LEF1; AIRE; MAK; CALCOCO1; REL; ALX3; SOX5; NFIX; BCL11A; SALL2; CRTC1; BACH2; PRRX2; TAF1; RBFOX2; ZNF556; RBPJL; PLAG1; ZIC1; GATA4; DNMT1; IFNB1; ZFHX2; RARG; CAPN15; CBX2; CBFA2T3; TAF5L; TLE2; VAX2; PBXIP1; CSDC2; NRL; RAX; PDX1; WNT4; NKX6-1; PRDM14; TGIF2; HOXC4; ATN1; SSX3; SOX13; TAF1C; PEG3; FOXH1; EZH1; HINFP; ZBTB16; PITX3; ZNF500; NR4A3; PROX1; TCF3; HIPK1; ZNF589; IKZF4; SPDEF; PAX9; MTA2; SUPT7L; ZNF124; BNC2; HIF3A; ZKSCAN3; GATA1; ZFX; LZTR1; ZNF423; TRIM25; NEUROG1; HOXB13; VENTX; MAPK8IP1; FOXF2; INSR; MEIS2; NOCT; SIX6; ZNF394; FOXN1; JUN; GBX1; YAP1; CUX2; TCFL5; ZNF79; ID4; ZNF710; ASH1L; ZNF816; NEUROD2; PAX1; CDK9; ZNF562; HIPK2; TSC22D3; ZNF202; KLF9; PRDM2; ETV2; ONECUT1; LHX1; ING4; PNRC1; KLF7; THRB; NKX3-2; GLI1; CERS4; ZBTB7C; ZHX2; ZNF74; NFYA; THRA; AEBP1; ZBTB44; ZNF76; ZBTB48; SSX7; PRDM13; ZNF623; ZNF467; GLI2; SRY; ZNF117; TBX19; PRRX1; GATA6; ZNF688; GFI1; ZNF219; GRIP1; E2F5; IKZF1; CREM; PRDM1; TP73; FOXJ1; HEYL; L3MBTL1; POU6F1; NPAS1; ZNF91; NEUROD6; TCF7L1; HOXB1; NHLH1; PGR; NR1I3; TULP1; TBX5; CEBPA; IRF7; SIX3; MYEF2; EHMT2; TEF; CDX4; RNF2; TLX3; TBX4; MAFF; PPARA; ZNF131; ZNF112; TFDP3; BANP; ZFP37; SNAPC4; EMX1; ZNF75D; ATF7; ARHGAP35; PRDM10; ALX4; JAK2; ZNF770; ZNF667; DLX4; ZBED1; ZNF221; ARL2BP; ZNF107; PAX7; KLF1; AR; COPS5; ETV3; GBX2; LHX2; ZNF235; FOXJ2; HLX; NR5A2; IRF6; OLIG2; MYOG; HOXC11; REPIN1; PAX3; AFF3; SCRT1; RAD21; NKX2-1; ASCL3; POLR3C; DMTF1; POU4F1; ZNF250; TULP2; NR6A1; ZNF93; ERBB4; ZNF337; CD3D; ZIM2; ZNF257; ZNF32; TBL1Y; MYBL1; SOX14; ZNF512B; HOXD13; HOXA6; ZNF253; KLF11; ZNF696; LMCD1; PBX3; ZNF324B; YY1; ZNF669; TULP3; ZNF3; SOX18; ZNF778; PRDM9; UTF1; TBX21; ZNF239; CDX2; ZNF286A; ATOH1; KDM4C; NANOG; SOX21; NEUROG2; NR0B1; MYCL; POU6F2; ZNF177; FOXE1; ZIC3; BCL6; HESX1; ZNF711; MED20; HDAC4; MYB; NFATC4; TRPS1; PRMT2; NR2F1; GRHL2; ZFPM2; TGFB1I1; SHOX; FEZF2; PRDM5; NFX1; SOX11; ZBED2; ZNF154; ZNF549; ARID5A; HES2; ZNF135; EPAS1; FOXE3; POU3F4; ZNF287; ZNF85; TFAP2A; ZNF132; SOX3; SMARCD3; ZBTB3; ZNF345; CREBL2; ZNF665; FEV; ZNF507; ST18; TBX1; ZKSCAN4; ZNF573; OVOL2; FOXA2; TRIM22; NFIC; ZNF33B; MED17; AGO2; ZFHX3; CBL; STAT4; MYF6; PITX1; ATF5; MDM2; RARB; CHD2; ZNF532; ZFP2; BRDT; MKL2; HDAC5; CTBP2; VPS72; ZNF391; SIM2; SP4; RFX3; JUND; ZNF426; EN2; ZNF34; POU1F1; PAX4; ZXDC; ZNF22; ZNF695; MNDA; TFEB; OVOL1; DCC; FOXL2; ZKSCAN8; POU2AF1; BHLHE41; ESRRG; KAT2B; AIP; ZNF232; TCF7; TFCP2; NCOA2; NEUROD1; RARA; NR0B2; FUBP1; HEY1; CIITA; TBR1; FOXF1; CREB1; IRF8; FOXO1; WT1; SCAI; CIR1; TAF4B; EP300; ZNF506; CRYM; FOXN3; SSX1; ZNF814; CARF; KLF8; ZNF214; CBX4; ZNF362; STAT2; ZNF324; LIN28A; THAP11; ZNF334; EYA1; VDR; ZNF780B; NFE2L3; HIC2; ZNF141; KLF3; POU5F1B; NR3C2; ZNF682; RXRA; ZNF208; CERS6; MDM4; NR4A2; SATB2; SPIB; CBX7; IRF4; BRD4; ZFP69B; ZNF492; VGLL1; TBX3; EN1; ZNF273; OSR2; INSM1; MED14; TOX3; ARID5B; SOHLH2; TCF21; TCF4; TCF7L2; ZNF331; TFAP2C; HHEX; NKX2-2; STAT1; BTG1; ZNF165; JUP; ZNF44; ZSCAN18; BNC1; MEF2C; IFI16; PAX6; EGR2; ASCL1; ATF3; ARNT2; ESR1; SOX9; TXNIP; SSBP2; TLE4
Down-regulation 129 SNW1; FOSL1; EGR1; TP53; TSC22D2; NUP62; ENO1; WWC1; MYCBP; RNF6; ZMYM2; SMAD3; TBP; CRK; FOXC1; FHL2; USP22; SMARCA4; HNRNPD; RUVBL2; ZBTB38; BASP1; ZNF468; C1D; HOXB7; CBX3; HLTF; DRAP1; SFPQ; PCBD1; TRIM28; AATF; ELK3; APEX1; SUV39H1; BMI1; SCAND1; BCLAF1; BBX; DDX54; BAZ1B; ORC2; HSF2; REST; HOXB6; YBX1; FLNA; NPM1; ADNP2; ERBB2; RBM14; USF2; NACA; RERE; NONO; PPARGC1A; SSRP1; PSMD9; C1QBP; SMARCE1; ZNF148; MSX1; TSC22D1; HMGB1; SMARCA5; UBP1; CTR9; MED1; COPS2; DNMT3B; RNF10; TFAM; BRD8; CBFB; KAT7; KLF10; MEIS1; GATAD2A; SMAD2; MBD2; HOXC6; HMGN3; DNAJC1; TRIB3; SMARCC1; SMARCA2; CARM1; ZBTB20; AFF1; HSBP1; SUB1; JARID2; YWHAB; CENPF; TAF10; DPF2; NFYC; ID2; NFIB; ID1; HOXA10; ZMYND8; ZNF146; MITF; PLAGL2; FOXJ3; RAN; ZNF586; ITGB3BP; PURA; HTATIP2; SMARCC2; EDF1; MEOX2; DDX5; ZNF587; ETS2; MYC; TOB1; SUZ12; PUF60; PSIP1; CARHSP1; NR2F2; PTTG1; HDAC1; MAGED1; NR1D2; NFATC3