Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09466 Azd-8330 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 354 SUPT3H; AFF2; UBE2L3; TLE2; PITX3; BCL11A; KLF13; ZBTB16; E4F1; YAP1; GATA1; TAF9; HINFP; LHX2; NFE2; ZNF219; TAF6L; SETDB1; IRF7; IRF1; ZFPM2; SOX5; SALL2; SOX2; MAFF; CREM; NRL; PROP1; NR1H2; PEG3; TRIP11; NEUROD2; MAP3K10; KLF9; TUB; RBFOX2; ZNF688; HDAC11; HBP1; ZNF33B; RING1; FOXF2; NCOA2; RSF1; CBX2; CEBPD; NR1H3; BCL6; CBFA2T3; HEYL; MEIS2; ZNF75D; CREB3; LYL1; AIRE; PRRX2; TGIF2; NFIX; ZNF771; SMAD7; ZNF282; BATF; CUX2; ZNF816; NKX2-1; FOXA2; NPAS1; IFNB1; KLF15; THRA; TRIM24; HIVEP3; RARG; AFF3; HDAC5; HOXA3; ZNF76; MED20; CEBPZ; PLAG1; PMS1; BANP; ZHX2; IRF9; REXO4; NCOA3; ZNF552; E2F5; ST18; VAX2; NKX6-1; TP73; HIF3A; PNRC1; ZBED2; SOX13; LZTR1; SPDEF; NEUROG1; NR4A2; PAX1; ID4; ZSCAN16; TAF1; AEBP1; FOXH1; PRDM14; ZNF589; CDC5L; NFATC4; LHX3; TRPS1; RFX1; RFX2; BARX1; ESRRA; ARHGAP35; ALX4; TDP2; ATF3; CBFA2T2; RORC; NR2F6; ONECUT1; ZNF74; ALX3; FOXJ1; ZNF239; PRRX1; SPI1; NHLH1; POU5F1B; TULP3; GFI1B; NR4A3; NKX3-2; ARID5A; MED12; SOX21; HEY2; CCNH; HESX1; ZNF444; PDX1; THRB; BRWD1; SOX17; POU4F3; IKZF1; CDIP1; PRDM5; TAF5; TGFB1I1; HOXD13; PRDM2; SCRT1; HOXB13; FEZF2; PAX7; TBX4; RORB; ZKSCAN4; OVOL1; TOX; WNT4; TLX3; MAK; TULP2; GLI2; ZNF117; DLX5; CEBPA; GLI1; MXI1; GRIP1; ZNF154; TEF; ZNF202; HSF4; ZNF232; ZIM2; FOXF1; MECOM; FOXE1; EMX1; CHD2; HIRA; TFDP3; AR; HHEX; ZNF124; DACH1; FOXK2; BACH2; ZSCAN31; ZNF710; TCFL5; PRDM12; SRCAP; ZNF778; INSR; ZNF423; SOX10; NFATC1; ATF5; PTRF; ETV1; ATN1; SREBF1; MYRF; TBX5; ZNF93; ZIC1; ARNT2; TRIB3; SOX3; LIN28A; HOXB8; CREBL2; NEUROD6; GATA6; ZNF331; PBXIP1; ZNF835; ZKSCAN3; NANOG; PBX3; POU6F1; TFAP2A; CERS4; KAT2B; CIITA; POU6F2; CARF; UTF1; ZNF235; PBX1; SMAD6; VPS72; ZNF177; ARID3B; ZNF623; REL; KLF1; SOX14; POLR3C; PRPF6; CRYM; ARRB1; IFI16; HLF; PAX6; PRDM9; ZNF415; BNC2; VGLL1; JAK2; SATB2; CBX4; KDM4C; BHLHE41; IRF6; NFX1; ETV3; MKL2; EPAS1; PREB; FOXE3; PRDM10; ZNF711; PRDM1; ZBTB48; STAT2; TCF21; EZH1; CDK8; ZNF22; SSX7; PPARG; TCF7L2; STAT1; WHSC1L1; ZNF85; HIPK2; ZNF500; ZIC3; FOS; KLF5; ZNF165; ASH1L; RARB; ZBED1; SPIB; VENTX; PPARD; ZBTB44; ZNF654; EHF; FOXN3; SRY; ZNF573; ZNF257; PAWR; NLK; SMARCA1; PKNOX2; SIX3; TAF5L; ZNF394; GRHL2; PAX4; MED14; ZNF695; ARID3A; POU2AF1; ZNF467; ERBB4; HOXA2; KLF3; MYCL; TAL1; MYT1L; TRIM22; ELF3; ZNF667; IRF4; GFI1; SATB1; ZNF141; TCEA1; PROX1; NR5A2; FHL5; IL16; CTBP2; ID3; NKX2-2; EN1; TBX3; ZNF665; MEF2C; AHR; HOXD1; FLI1; OLIG2; TOX3; CALR; KLF4; ZSCAN18; HIC2; MYB; TFAP2C; NEUROD1; THAP11
Down-regulation 160 MYCBP; FOSL1; TSC22D2; MTF2; SFPQ; EGR1; TCERG1; NPM1; MED6; ATF1; HSF2; HNRNPD; SMARCE1; BAZ1B; KAT7; BCLAF1; CRK; TBP; NFYC; YWHAB; ZNF432; SUB1; FOXJ3; NACA; REST; MED1; BCL11B; TP53; APEX1; SNW1; NRBF2; RBBP4; KLF10; PRKDC; CRY1; USP22; TRIM28; RBBP5; HOXC6; CBX3; JARID2; NUP62; HMGN3; HMGB1; POLR2A; RBM14; CENPF; ORC2; RAN; EZH2; HLTF; MED24; SP3; SMARCD1; FOXD1; FLNA; YBX1; ZNF468; NRIP1; AATF; SMARCA4; SUV39H1; HOXB6; ZNF134; NFE2L1; GATAD2A; ADNP2; BRCA1; HDAC1; BTF3; SP2; TBL1XR1; ZNF23; ZNF146; RNF6; RNF10; USF2; C1D; PA2G4; MAZ; VGLL4; BMI1; CTR9; ACTL6A; HIPK3; KAT5; CEBPG; ENO1; RCOR1; HOXA10; CBFB; SND1; UBP1; TRIM32; ZNF14; YBX3; NR2F2; ZNF266; SMAD2; SPEN; CBX5; ID2; EDF1; RUVBL2; NEDD8; NFIB; PCGF2; AFF1; CARHSP1; MYCN; ATF7IP; ZNF419; TBPL1; SMARCC2; NONO; ELK3; ZNF226; CTNNB1; MYC; PHOX2B; BRD8; MLXIP; NCOA6; SMAD1; SOX9; ETS2; KLF2; PSIP1; LZTS1; TBL1X; FOXC1; CEBPB; TAF1D; TSC22D1; MAFB; DPF2; NCOA4; MITF; EGR3; MSX1; MED23; DEK; ZNF551; SUZ12; NCOR2; EMX2; NKX3-1; ETV5; ZNF217; HSBP1; SNAI2; PLAGL1; HTATIP2; ERBB2; ASCL1; MEIS1; CITED2; ZBTB38; ZNF586; NR3C1