Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09465 Azd-8330 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 99 IKZF1; NFKBIA; SP110; IRF9; TRIM29; ADRB2; SP140L; HBP1; TRIM22; RING1; IRF7; FOXN3; UBE2L3; IRF1; RHOA; NFE2; GLI2; TGFB1I1; ATF4; TP63; MXI1; STAT6; FOSL2; KAT6B; BCL6; LEF1; HLF; BATF; KDM5D; CREB3L1; KLF7; STAT1; RORA; TRIM16; ZIC1; NFIC; ZBTB16; NFIL3; CSDC2; SHOX2; PITX1; TWIST1; SIAH2; CD3D; DDIT3; ZNF654; KLF13; SSX1; STAT2; FOXF2; HIVEP1; NR1H2; RARG; STAT4; SOX5; ZKSCAN4; TBX1; ID4; MAFF; HIRA; FOXO1; PRDM2; ZFPM2; SMARCD3; SMAD1; VPS72; OVOL2; JAK2; EYA2; ARID5B; ZNF91; TRIB3; SOX11; ZNF232; LPIN2; ZNF467; HEY1; ATF3; KAT2B; SPDEF; TXNIP; ZHX2; AEBP1; ZNF117; GATA6; ZFP36L1; ZBED2; PAX6; OSR2; ZIC3; ZNF665; KLF9; FOXG1; BNC1; PEG3; ERBB4; ZNF589; IRF6; ZNF586
Down-regulation 58 EGR1; FOSL1; BCLAF1; MTF2; ARID4B; CHD1; HMGA1; HMGA2; ORC2; ZBTB1; BMI1; RCOR1; TFDP1; BASP1; FOSB; CTR9; CENPF; HNRNPD; ELF1; HTATIP2; RFX5; PHIP; AFF1; ELK3; TULP4; CBX3; ATF5; RNF4; TOB1; NR4A1; ZBTB20; TBL1XR1; NR2F6; SCAND1; EDF1; ESR1; BBX; EGR4; NR2F2; TSC22D1; PCGF2; DACH1; DNMT3B; EGR3; NR4A2; NKX2-2; HOXB7; ID1; CHD7; ZNF721; HLTF; CITED2; MED1; IRX5; CEBPZ; ZBTB38; HOXC6; PPARG