Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09464 Azd-8330 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 187 HBP1; NFIC; KLF7; MAML1; TCF3; SRCAP; ZBTB16; PRRX2; CRTC1; SP140L; RING1; MED12; ATF3; HOXB1; TULP3; PITX3; PBX2; CEBPB; SUPT3H; ETV6; HLF; SMAD6; HSF1; KLF13; BCL6; SIRT7; MXI1; LHX2; LHX3; FOXJ1; RORC; ZNF232; TSG101; MED25; CEBPD; SOX2; MKL2; YAP1; PEG3; TRIB3; ELF4; FOXF2; NHLH1; RBFOX2; GATA1; ZBED2; ZNF500; OVOL1; EZH1; STAT5A; RARG; ARNT2; FOXK2; PSPC1; HINFP; SOX13; SSBP3; ID4; TFAP2A; ARL2BP; NFIX; TP73; JUND; LITAF; TEAD3; MAFG; NRL; ARNTL2; PBXIP1; SOX5; CBX2; NR1H2; HMBOX1; MEIS2; NR2E1; CCNH; HSF4; PKNOX2; FOXO1; HIRA; KLF9; DDIT3; SPDEF; ZNF654; LPIN2; PAX6; HOXD1; MED17; BARX1; GATAD2A; ELF5; KLF5; ZSCAN9; SOX9; HIC2; NFATC4; TCF7L1; ZNF688; NKX2-1; ZXDC; OVOL2; TCFL5; FEZF2; FOXI1; RXRA; PRRX1; SOX3; VGLL1; KDM5D; PAX9; PNRC1; NEUROD6; TCEA1; DLX5; E2F8; TRPS1; EPAS1; GLI2; NR2F6; JAK2; ZHX2; ZNF423; SRY; PLAGL1; TFDP2; CD3D; PRDM14; NEUROD1; PRDM2; TDP2; IRF9; TGIF2; HIPK1; EN1; SOX18; VPS72; TOX; FOS; SOX21; MYRF; ZFP36L1; ZIC3; SMARCD3; ATF4; STAT4; BNC2; SPIB; FOXG1; ZNF124; EYA2; ZIC1; ZNF217; PITX1; ZSCAN18; TCF7L2; ID1; MECOM; HDAC5; ZNF117; PBX3; SNAI2; HIPK2; TWIST1; SOHLH2; SALL2; ZNF711; HOXB2; KLF11; LIN28A; PBX1; CUX2; ZNF589; THAP11; ZNF264; KLF3; CBFA2T3; MAFB; CEBPA; ST18; IRF6; SOX11; ZNF91; AEBP1; ERBB4; TFAP2C; WT1; IKBKAP
Down-regulation 109 EGR1; ATF1; ZMIZ2; BCLAF1; BMI1; BASP1; FOSL1; MED6; ELK3; SFPQ; MTA1; SNW1; HNRNPD; KLF6; ING3; AATF; C1D; CBX3; ZNF146; RBM14; ZNF432; HSF2; SUB1; ZBTB24; ZBTB38; HMGA1; HMGA2; HOXB6; ARID4B; EDF1; UBP1; PATZ1; AFF1; PCGF2; MED1; APEX1; RFX5; MTDH; PQBP1; TCEB2; CCDC59; KMT2A; ID2; HOXC6; SSRP1; RCOR1; CERS6; NPM1; KAT6B; SCAND1; NEDD8; IL16; TFEB; ZBTB1; SP3; CREB5; DDX54; USF2; EZH2; DNAJC2; KLF10; ZNF468; DACH1; CTR9; CBFB; HDAC1; ENO1; BCL11B; CREBZF; REPIN1; ZNF516; HOXB7; TCF12; YBX1; ZFHX4; MYC; CCNC; POLR2A; CRY1; TRIM28; MAGED1; BAZ1A; ZNF721; MED23; ZEB2; PHIP; SAP30; ASCL1; BAZ2B; BIRC2; YWHAB; ETS2; ZBTB20; MNDA; BBX; RUNX3; ACTL6A; HMGB3; FLNA; ESR1; IRX5; CEBPZ; ZNF302; HTATIP2; POU2AF1; ZNF160; STAT1; NR2F2; MYB