Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09458 Cgp-60474 GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 593 EGR1; SIX5; E2F4; GBX1; HOXC5; ZNF816; TWIST1; RSF1; NR4A2; RAX; MED31; AR; NR4A1; TAF6L; RFX1; TONSL; ATF6B; HDAC11; SOX17; THAP10; PROP1; MZF1; NR2E1; WNT4; ELK4; POU3F2; ZSCAN2; SSBP3; CEBPE; TCEA2; SHOX2; LHX6; IRF1; NFKBIB; CRTC1; TGFB1; LMX1B; MXI1; NKX2-5; TLX2; MAPK8IP1; ZNF528; CEBPD; LDB1; EHMT2; HOXB1; CAMTA2; HAND2; MYNN; SPI1; FOXJ1; ZFHX2; NFIX; MEIS2; DBP; ATF3; FOXF2; ZNF536; FOXF1; ZNF205; SP140L; CDX1; ZNF75D; RBPJL; MECP2; ACTL6B; CD3D; OVOL2; HIF3A; MYCL; HDAC9; MLLT1; HEY1; NEUROG1; SOX1; ESRRB; ZFPM2; PBX2; NFE2L2; YAP1; HEYL; NR4A3; TBX6; NPAS1; SOX2; ZNF771; ZNF91; FOSL1; SKIL; ALX3; CDX4; ZNF557; ZBTB7B; NR5A2; FEZF2; TUB; ZNF350; HOXD3; KMT2D; ALX4; SRCAP; TULP1; ZNF35; VSX1; HIVEP3; LHX3; PRDM12; ZNF274; ZNF180; PFDN5; FOXP3; NKX2-8; CBX7; BHLHE40; CNOT2; HIC1; HNF4A; MYRF; CARF; ZNF331; ZNF8; ZNF222; FOXG1; HOXD1; NEUROG3; ONECUT1; FOSB; ZNF195; ZNF358; FOXL1; BCL6; ZNF556; ZNF835; NR5A1; ZNF354A; SCRT1; PRDM1; ID1; MAML3; ASCL3; HIPK2; VENTX; THRB; PITX3; REL; GBX2; ZNF787; CRX; BAZ2A; PAX3; TEF; RORA; DLX2; ZSCAN9; ZNF136; LMO1; SSX3; SOX3; KLF13; ZNF221; AFF2; DOT1L; C1QBP; ZNF770; ZXDC; PPARGC1A; SALL2; PAX6; RBL2; HBP1; LZTR1; HOXC8; ZNF225; TAF1; CERS4; SRY; CBX4; EPAS1; HOXB5; NEUROG2; ZNF623; ZNF223; FOXD3; ZNF345; TBX4; MED12; MAFK; HAND1; HLX; ONECUT2; IFI16; PDX1; SOX18; POU3F3; SIN3B; ING4; ETV2; SOX5; NEUROD2; RFXAP; CREB5; ZNF580; NEUROD4; ZNF235; SMARCA4; ZNF154; ZNF264; FOXB1; KDM4C; NACA2; ASH1L; RING1; ATOH1; NKX6-1; CREG1; FOXA1; CAMTA1; GON4L; ESR2; ZNF549; TP73; KAT6B; CUX2; HOXA3; MEF2D; MECOM; BPTF; ZBTB43; ZNF701; SIX6; NFIC; PAX7; ZNF219; ZNF76; EVX1; KAT2B; PHF1; BCL11A; ZNF174; AFF3; CALCOCO1; GRIP1; PRDM16; KLF15; ZNF287; PPARA; ZNF606; ZXDB; BRDT; GSC2; NR1I2; IKZF2; TFAP2B; NEUROD6; HMBOX1; IKZF4; ERCC2; PHOX2A; NR1I3; LBX1; RORC; TFAP4; CBX2; ZNF215; NR1H4; TEAD3; VGLL1; SUPT7L; SCAI; ETV5; HHEX; MED25; PRRX1; HLF; ZNF695; PRDM9; HMGA1; POU4F3; GCFC2; HOXD12; ESR1; DLX6; HOXD13; SOX14; SOHLH2; TBX5; HESX1; TAF9B; PAX1; TLX1; ETV1; PRDM14; ZNF480; ZNF43; ARNT2; ZNF711; LHX2; HNF4G; E2F2; NCOA3; CHD2; RORB; FOXA2; ZFY; SOX21; ZNF552; TBX10; HOXD11; SNAI1; BARX1; EP300; MAK; MAP3K10; ELF3; FOS; ZNF671; ZKSCAN8; ATN1; ZNF467; DCC; ZNF778; ZNF423; OVOL1; POU6F2; CIITA; TBR1; CREBL2; ZNF14; ZNF253; TAF7L; ZBTB39; SSX7; TCF21; TBX21; AIRE; NFE2; TRIM24; ARRB1; TSHZ2; HOXB8; HOXD10; ZBTB3; ZNF304; SOX13; ZNF688; ZKSCAN4; ZNF667; ZNF551; PRDM2; IRF2; ZNF550; SUPT6H; ZMYND11; ZNF10; TBX19; RARG; ZNF814; SHOX; EMX2; ZNF544; GLI3; RFXANK; CIC; HMX1; BRWD1; LYL1; AFF4; INSM1; NRL; HES2; HSF4; EMX1; MYEF2; NOCT; FOXH1; MKL2; PBXIP1; ISL1; ZNF93; ZNF442; ZBTB6; TAF4B; ZNF407; POU2F2; ZNF224; ZNF124; DMRT1; IFNB1; ZNF155; ZKSCAN1; CNOT3; ZNF749; ZBTB20; HDAC5; ZNF562; PKNOX2; BHLHE41; TLX3; ZFP2; ZBTB48; NHLH1; CBFA2T3; BCL3; NR0B1; ZNF674; EGR4; ZNF44; ZNF80; SP140; ST18; SALL1; NHLH2; ZKSCAN3; ZNF471; ZNF682; SOX15; GTF2I; CDIP1; IKZF3; ETV3; ZNF41; FOXN1; ZNF254; SLC2A4RG; TFDP3; ATF7; MEOX1; OSR2; THAP9; ZNF507; FOXE3; L3MBTL1; ZNF500; WWP1; POU3F4; ZNF529; ZNF74; ZNF85; ZNF140; ZBTB7C; KLF11; KLF7; ZNF343; MAFF; CNBP; POU1F1; IRF3; ZFP69B; PPARG; TFAP2A; ZNF112; ZNF132; ZNF107; KLF8; IKZF1; STAT4; ZNF81; UTF1; ZNF484; JUNB; POU4F2; THRA; ZNF391; CREM; POU2F3; NKX3-2; MEOX2; GFI1; SSX1; ZNF157; IRF6; SIX3; SNAI2; TBX1; RFX3; SUPT3H; PAX4; TGIF2; PRDM5; VHL; PITX1; TULP2; ERBB4; GCM2; ZNF675; EZH1; TRIM22; MSX2; ZNF117; GRHL2; RARB; ZIC4; ZNF214; MEIS1; ZNF208; EGR2; IRF8; ARID3B; ZNF573; ZNF362; TRIB3; SATB2; ARID1A; AHR; ZIM2; HEY2; MYT1; ZNF177; ZNF780B; HOXA2; NR0B2; ZNF34; ZNF257; FHL5; ZNF134; ZNF211; ZNF239; MNDA; PNRC1; ZNF611; ZNF415; MDM4; ZNF492; CITED1; ZNF493; ZFHX4; IRF9; MYC; SOX11; NR1H2; ZNF273; ZSCAN31; GATA6; NR2F1; ZNF710; ZIC3; ZNF334; NR1H3; CALR; PBX1; PIR; INSR; SP4; ZNF440; SPDEF; SMARCA1; JUN; NFATC4; BNC2; TRPS1; STAT2; TAL1; PEG3; CREB1; HES1; MDM2; NKX2-2; ZBTB44; HDAC4; ZNF232; EYA2; TFDP2; ZNF141; NR1D2; MYT1L; ID3; TOX; ZNF394; VPS72; CRYM; KLF3; KLF9; EGR3; MEF2C; TXNIP; WT1; NEUROD1; TADA3; CEBPB; LIN28A; HOXB2; ZNF665; ZFP36L1; HIC2; GATA2; BNC1; TCF7L2; TBX2; GATA3; AEBP1; NFKB2; THAP11; MSX1
Down-regulation 164 HOXA5; CCNA2; XBP1; FHL2; NUP62; ECD; PAX8; USP22; UBE2I; ATF1; SNW1; FOXO3; SMAD3; TCERG1; SUV39H1; TRIM29; NFIL3; RBM14; SMARCE1; TAF9; BCLAF1; CRK; HNRNPD; SMARCA5; GTF2A2; CDK7; BRCA1; EZH2; RNF111; KAT7; TLE1; RBBP4; PATZ1; CENPF; DNAJC2; SFPQ; CRY1; ING2; TBP; PUF60; GTF2IRD1; BLM; CCNC; NFE2L1; NPM1; AATF; PQBP1; RNF6; CNOT6; CDK2; SOX4; BRD3; HOXC6; PSMC3IP; RBPMS; CNOT1; DNAJC1; PSPC1; TBL1XR1; MED6; ZNF672; NCOA6; NPAT; MBD2; DEK; RBPJ; ITGB3BP; TRIM16; ZNF146; TCF12; BASP1; NELFB; BAZ1A; HOXC10; PHF2; CENPB; MAGED1; TBL1X; HOXA10; BMI1; MED24; ELK1; CHAF1B; EDF1; NRBF2; RNF138; REPIN1; KLF6; SF1; UBE3A; ZMIZ2; ZMYM2; AFF1; RAN; PMS1; ATF5; HMGB2; CBX3; HOXB7; SMARCA2; MLX; PCGF2; TRIM32; STAT3; DR1; SAP30; MED1; TCF20; ELF1; FOXJ3; NCOR2; WHSC1; CTBP2; ZBTB11; MTDH; TFAM; CREB3L1; COPS5; RBBP7; ATF4; IRF7; SIAH2; ZNF281; NAB1; HMGB1; PHF20; ZNF302; TBPL1; EED; CCDC59; STAT6; DNMT3B; NCOA4; BRD8; MED7; HDAC2; MEF2A; ENO1; VEZF1; ABL1; DDX17; NR2F2; YWHAB; SMAD2; CBFB; XRCC6; PTTG1; KAT6A; ELF5; TAF1D; NKX3-1; NONO; DDX5; CEBPZ; ERBB2; STAT1; RUNX1; PBX3; ZBTB18; RFX5; BTG1; ETS2; MYB; ZNF586