Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09457 Cgp-60474 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 640 EGR1; NFKBIB; FOXJ1; LDB1; RSF1; MYNN; AR; ELK4; ZNF816; E2F4; SIX5; NR4A1; ZNF528; HDAC9; HOXC5; TRIM33; HAND2; KAT6B; MZF1; NAB2; ISL1; TONSL; SHOX2; ZFHX2; NFAT5; PROP1; NKX2-5; EMX2; ZSCAN2; HMBOX1; WNT4; GBX1; HHEX; HLX; ZNF75D; SOX17; ACTL6B; DBP; ZSCAN32; TCEA2; SUPT7L; LMX1B; CDX1; PBX2; BAZ2A; CAMTA2; ETV1; HIF3A; SP140L; THAP10; FOXO4; NR4A2; ZNF205; MED31; ZNF835; GON4L; CALCOCO1; RFXAP; EHMT2; MECP2; ZNF180; ZNF345; ZKSCAN1; RFX1; PHF1; TLX2; NR2E1; LHX6; HESX1; SKIL; MEOX2; SETDB1; ZNF423; TWIST1; POU3F2; MEIS2; ZNF195; SOX2; SPI1; ZFPM2; NR0B2; OVOL2; MAK; HBP1; BCL11A; ZNF623; CAMTA1; JUP; NKRF; ALX3; MAPK8IP1; ZNF331; REL; ZNF529; FOXA1; ZNF222; ZNF536; DLX2; ZSCAN9; RBL2; TBX4; FOXF1; SOX3; CEBPE; TAF1; PDX1; ZNF268; RBPJL; ZNF3; CARF; SIX6; MED12; RORA; HNF1A; ZNF354A; ZNF770; HDAC11; ONECUT1; ZKSCAN5; NEUROG1; ZNF8; BRWD1; PRDM1; ATF6B; HNF4A; ZNF136; SOX1; NFIC; ZNF225; ZBTB3; NHLH2; SMAD5; FEZF2; ZKSCAN4; HSF1; INSM1; HMX1; MYCL; ESR1; MAML3; POU4F2; MYCN; PITX1; TAF6L; TLX1; ZNF562; SSBP3; ZKSCAN8; PPARA; FOS; HOXD1; ZNF701; SOX18; SKI; HMGA1; ZNF500; SOX5; ZNF646; ZNF253; ASCL3; MED25; ZBTB39; MLLT1; ZNF264; HOXB3; TAF4B; FOXN2; RAX; TCF21; MEIS1; SSX3; VSX1; ZNF671; RXRB; WHSC1L1; ZFP30; NR1H4; ZNF107; ZNF287; HOXC4; CBX7; PAXBP1; GABPA; ZNF695; ZNF223; ASH1L; ZNF350; NR2F1; CIITA; HIPK2; HOXD3; PFDN5; HINFP; EP300; HOXD13; SIN3B; NR4A3; ZBTB7B; ESRRB; HOXB5; ZNF76; BRF2; EMX1; DMRT1; PKNOX2; SALL2; IKZF2; PHOX2A; TFAP2B; STAT4; TEAD3; NEUROD4; ARNT; NR2C1; RING1; CDX4; TBX6; FOXG1; ZXDC; THRA; ETV7; MYRF; CHD3; NR5A1; VGLL1; ZNF557; HIVEP3; MLXIPL; AFF4; ZNF771; DOT1L; PAX7; CBX4; ZNF467; CUX2; ZNF221; SP1; TRIM22; NR5A2; GRHL2; IRF6; SRCAP; ARID1A; LZTR1; CNOT3; ZXDB; SMARCA4; ZNF174; HEYL; CRX; TULP1; NFIX; SP140; BPTF; ST18; ZNF79; FOXB1; SCRT1; LHX3; NACA2; HLF; SCAI; VENTX; CBFA2T3; PAX3; ZNF23; TFAP2A; MYT1; CCNH; ARHGAP35; HAND1; PHF8; ZNF304; ZNF552; PNRC1; NEUROD6; TRRAP; ZNF480; ING4; ZNF124; ZBTB48; TRIM24; PLAGL1; RORC; TEF; MECOM; ATOH1; TP73; MYEF2; TFAP4; L3MBTL1; ZNF85; ALX4; ZNF154; ZNF573; CHD2; PRDM16; THRB; ZNF274; ZNF556; ZNF814; ZNF235; ATF7; NCOA3; HSF4; BARX1; NPAS1; ZNF544; ZNF787; BRDT; PEG3; TBL1Y; TSHZ2; IRF3; ZNF22; MEF2D; NHLH1; ZNF549; PRDM10; RORB; GTF2I; PRDM9; FOXF2; AFF2; TRIM25; NKX3-2; DCC; NKX6-1; HIC1; PAX1; PRMT2; TRIB3; CIC; ZNF33B; KMT2B; SRY; ZFY; HMGXB4; ZNF749; LHX1; ZNF484; CBX8; TBR1; ZNF224; ZNF492; NR6A1; EGR4; IKZF3; MDM4; FOXD3; WDR77; OSR2; ZNF675; EYA2; KLF11; ERBB4; GRIP1; NEUROG2; SSX7; ZNF215; NFE2; ETV2; ZNF606; ZNF407; NEUROD2; ZNF471; POU2F2; HOXB1; MXI1; SUPT6H; PAX6; ESR2; SOX14; ZNF10; TAL1; CD3D; TBX19; FOXA2; ERCC2; ZNF117; CREG1; CCNT1; ETV6; AFF3; THAP9; CDIP1; ZNF286A; MLXIP; TBX5; HOXB8; ARRB1; GSC2; ZNF571; ZFP37; RFX3; KDM4C; SOHLH2; CERS4; ZNF232; MYF5; PRDM12; RCOR3; ZNF682; ZNF674; VPS72; SIM1; ZNF184; ZNF80; SUPT4H1; ZNF334; CBFA2T2; ZNF14; ZNF155; INSR; ZNF43; ASCL2; PRDM2; PROX1; POU4F3; HOXD12; ATN1; PRDM14; ZNF41; ZNF667; YBX2; TRAF6; PRDM5; ZBTB44; PEX14; ZNF157; KLF13; ZNF132; HNF4G; TOPORS; EGR3; HOXD11; NR1I2; SOX13; ELF3; KLF15; SOX11; ZBTB6; PHOX2B; ZNF254; ZNF415; KDM5C; IRF8; ZFHX3; CBL; TRPS1; ZNF550; ZNF813; RFX7; MDM2; ZNF696; ARID5A; POU2F1; ZNF442; SHOX; CREM; TCF15; ZKSCAN3; ZBTB43; PAX4; SSX1; ZNF74; SUV39H2; HDAC4; FOXE3; ZNF711; TGFB1; YEATS2; E2F2; ZNF507; POU6F2; ZNF175; NR2C2; GCM2; ZNF273; TBX1; ZNF208; JAK2; ZNF214; ZNF141; VHL; ZNF343; FOXH1; SNAI1; ZNF362; ZNF493; TBX21; ZNF391; EZH1; EPAS1; PPARD; ATF3; ZNF710; ETV3; TULP2; RXRG; EHF; IKZF1; RARG; ZNF81; YEATS4; ZFP2; CEBPD; ZNF200; CREB5; GFI1B; ZNF257; TAF1C; IRF1; CRYM; HES2; PPARGC1A; TULP3; STAT2; POU4F1; ZBTB20; ZNF780B; GATA2; ZIC3; POU2F3; NFX1; RERE; ZNF580; POU6F1; NR1I3; LYL1; CREBL2; CUX1; ZNF778; NR1H2; ZNF239; GCM1; ZNF34; DLX5; FHL5; TGIF2; ZNF234; WWP1; GATA6; AHR; ZNF688; ARNT2; ZFP69B; BACH2; ZNF551; ZBED2; MEF2C; SP4; KLF8; GLI3; IRF2; PCGF3; ETV5; ZNF440; ZNF506; ZNF93; ESRRG; SOX21; AGO2; PAX9; ZSCAN18; NFATC4; POU1F1; TTF2; OVOL1; ZNF134; MKL2; PLAG1; WT1; UTF1; TAF5L; TOX; TERF1; ZNF211; ZFP36L2; OLIG2; CSDE1; SMARCA1; TLX3; NR0B1; SPDEF; HES1; PAX5; ZNF177; HEY2; ZIM2; SLC2A4RG; SIX3; KLF7; ZSCAN31; SUPT3H; ARID3A; PRRX1; NPAS2; TFDP2; TCF7L1; JUN; HEY1; TBX2; NEUROD1; AEBP1; ZNF44; KAT2B; BRD4; EYA1; CEBPB; BHLHE41; HOXB2; HDAC5; ZNF91; SATB2; ZNF532; ASCL1; BRD2; SNAI2; NKX2-2; IRF9; NFKB2; BCL3; NR1D2; TXNIP; FOXC1; ID3; ZNF611; EGR2; POU2AF1; ZNF83; CREB1; KLF9; DACH1; ZFP36L1; FOSB; MNDA; ZNF589; ARID5B; LIN28A
Down-regulation 176 HOXA5; CCNA2; FHL2; XBP1; CRK; NUP62; SNW1; USP22; UBE2I; GTF2A2; SUV39H1; RB1; ECD; RBM14; HOXA10; CDK2; BCLAF1; NFIL3; BASP1; HNRNPD; SMAD3; EZH2; SCAND1; CENPF; ATF1; PAX8; APEX1; SFPQ; CDK7; CHD1; PMF1; RBBP4; VGLL4; ING2; DNAJC2; PQBP1; RAN; BRD3; PUF60; MED6; TAF9; EDF1; TSC22D2; TP53; REST; KAT7; ZNF672; SMARCE1; CRY1; NPM1; CBFB; CENPB; TRIM29; RBM39; TCERG1; DDX5; NCOR2; TBL1XR1; ATF6; FOSL1; CREB3L1; YWHAB; KLF6; BMI1; EWSR1; NFE2L1; ILF2; REPIN1; CCNC; STAT3; NR2F6; TRIM32; TEAD4; PSMC3IP; ENO1; NRIP1; KLF5; FOXJ3; MBD2; MLX; HDAC2; HOXC6; SMARCA5; AATF; ATF4; NELFB; ELK1; XRCC6; MAGED1; TAF7; ID2; BLM; ZFP64; DEK; DNMT3B; PATZ1; TCF20; GATAD2A; SMARCC1; TRIM16; BRD8; PHF20; COPS5; CBX3; ZBTB11; NCOA4; RARA; GTF2IRD1; UBE2L3; ASH2L; ZNF146; PRPF6; DDX17; DNAJC1; NRBF2; PCGF2; HOXB7; HOXC10; RNF6; FOXM1; BRD7; HMGB1; DDX54; NCOA6; ASXL1; MAX; WHSC1; SSRP1; ZMIZ1; SF1; VEZF1; TGFB1I1; FOXO1; ZNF131; ZBED1; CTR9; ZBTB1; PTTG1; NEDD8; CEBPZ; RUNX1; TCF12; PSMC3; HSBP1; TRIP6; PAWR; COPS2; RNF4; CTBP2; NONO; TLE1; PURA; ELF5; ZBTB18; KLF4; STAT1; HMGB3; NPAT; ZNF266; SOX4; BTG1; TBL1X; FLNA; HMGB2; TAF10; IRF7; SOX9; SAP30; ABL1; AFF1; PBX3; MAF; NR2F2; THAP11; SSBP2; ZNF586