Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09456 Cgp-60474 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 437 EGR1; NR2F1; HMBOX1; RELB; CALCOCO1; LDB1; ELK4; MZF1; SETDB1; CD3D; FOXF1; TGFB1; DBP; ZNF205; NFIC; MED12; RSF1; ZNF580; FOXF2; MYRF; ZNF358; ZNF816; MEIS1; SPI1; CHD3; EHMT2; RBL2; MED15; MECOM; MEIS2; CREG1; NEUROG1; HOXB13; TCEA2; HSF4; MXI1; HLX; POU3F2; PAX6; CALR; E4F1; SOX17; GBX1; TWIST1; TONSL; ARID1A; CRTC1; CNOT3; CBX7; ZNF350; CERS4; FOXA2; RAX; HOXB3; ZNF75D; MXD3; NR1H3; HAND2; SIX5; RING1; PKNOX2; CDX1; TAF6L; PROP1; SLC2A4RG; ISL1; PBX2; NR4A1; HOXC5; ZNF268; HIF3A; ZNF444; AR; PRDM1; KAT2B; FOXJ1; NKX2-5; ZFHX2; ETV7; HOXB1; THAP10; CAMTA2; PEX14; LZTR1; RBFOX2; NR2E1; EVX1; TBX21; ZNF467; CNOT2; SSBP3; MEOX1; BARX1; HNF1A; EMX2; ZNF219; RORC; TLX2; WNT4; RBPJL; AES; PBXIP1; CBX4; ZNF500; ESRRB; PITX1; MXD4; PEX2; NR5A2; SIN3B; ZNF136; TBX10; ZNF768; ZNF274; MYCL; NR4A2; TULP1; NFKBIB; HOXD3; CRX; RORA; ZSCAN2; SOX2; ZNF76; KDM5C; MYNN; ZNF835; PLAGL1; ZNF528; TBX6; SALL2; NPAS1; MYT1; ZNF787; TEAD3; ZNF771; NFIX; EZH1; ALX3; ING4; NEUROD6; THRA; MAPK8IP1; CARF; ALX4; ZNF3; MYCN; HNF4A; ASCL3; STAT5B; SKI; OSR2; GRHL2; ZNF345; HLF; MECP2; ZNF623; SHOX2; TAF1C; ETV1; ATN1; CAMTA1; NEUROD4; HEYL; ZNF180; FOXG1; ZNF536; LHX2; ZBTB48; SUPT7L; TLE2; MLLT1; SP140; ZNF174; FOXO4; HOXD1; TERF1; RFX1; BRF2; ZNF248; ZFPM2; GATA1; HIPK2; IRF3; TBX4; TSHZ2; RHOA; GATA6; HMGXB4; SSX3; SREBF2; HEY1; ZNF8; CDIP1; ARID5A; ST18; LHX6; ZNF711; TP63; KLF15; ZNF14; PIAS1; BCL11A; PRDM12; IRF1; ZNF606; KAT2A; KLF7; ZNF671; TFEB; POU2F2; PDX1; STAT4; EP300; ZNF329; LHX3; TAF4B; CIR1; ZNF331; OVOL1; RARG; CIITA; NEUROD2; NR4A3; ZNF287; ZNF155; SOX18; ZNF419; GBX2; SOX3; CBX2; POU3F4; ZNF222; SOX13; FEZF2; HDAC9; ASH1L; ZNF304; FOXB1; HOXC8; BCL6; HOXD13; ZKSCAN3; ONECUT2; MEOX2; VPS72; ZNF415; MNX1; ERCC2; NKX3-2; ZNF813; ETV2; ZNF112; ZNF529; FOXA1; RORB; ZNF211; THRB; TEF; SOX5; ZNF423; CERS6; MYEF2; NR5A1; HAND1; MAML3; TCF21; ZNF254; SATB1; WWP1; ZNF12; SRY; IRF8; TFDP2; ZKSCAN8; PBX1; TP73; NCOA3; TXNIP; BCL3; CAPN15; FOXH1; ATF3; PHF1; ACTL6B; ZNF22; ZNF10; ZSCAN18; AIP; ERBB4; TBX5; REL; ETV5; TBR1; ZNF154; IL16; SOX15; ZNF34; NHLH2; ZNF688; EMX1; HOXC4; ZNF442; NEUROG2; PRDM14; DCC; ZNF589; ZNF701; WHSC1L1; PRDM9; ARID3B; SOX11; CHD2; ZNF778; ZNF571; CEBPD; DLX5; HDAC5; ZFP2; ZFHX3; ZNF552; POU2F1; PHOX2B; ZNF692; ZIC4; TRPS1; PRDM5; EGR3; HOXD11; ZNF695; RFX3; ZNF682; ZNF506; ZKSCAN4; SMAD5; LZTS1; VGLL1; OVOL2; TFAP2A; FOXI1; ZNF225; KLF13; NEUROD1; ZNF749; NR1H2; ZNF264; POU6F2; CUX2; SSX7; ZBTB3; ZNF573; PIR; RERE; TFDP3; ZNF215; ZFY; ZSCAN9; E2F2; ZXDC; NR1I3; CSDE1; KLF9; ZNF814; MDM4; SCAI; ZNF232; TCEA1; CITED1; ZNF235; IRF6; CHD4; L3MBTL1; SPDEF; MAF; RUNX3; NKX2-2; MDM2; ATOH1; ZNF43; LITAF; ZNF257; ZNF468; ZNF132; INSM1; SMARCA1; EN2; JAK2; AHR; GLI2; BHLHE41; ZNF532; ZNF135; PRDM2; SSX1; ZIC3; OLIG2; ZNF544; ZNF208; MSX1; ZNF273; ZIC1; SNAI2; ZNF141; EGR2; SIX3; HOXB2; ARNT2; ZNF611; ZNF667; LEF1; TRIB3; HIRA; ZNF83; IRF9; SP4; SPIB; BNC2; ESRRG; NFATC4; WT1; IKZF1; RFX5; TAL1; ESR1; TCF4; BRD4; ZNF117; KDM5D; MEF2C; TOX; SOHLH2; TBX2; ZBED2; GATA2; ZNF91; HIC2; PEG3
Down-regulation 197 HOXA5; CRK; XBP1; CCNA2; FHL2; ATF1; NFKBIA; TBP; USP22; NUP62; TCERG1; UBE2I; ATF5; MED6; BRCA1; FOXO3; TSC22D2; PAX8; FOSL1; SNW1; SUV39H1; PPRC1; PQBP1; SMARCE1; CNOT1; CBFB; HNRNPD; SFPQ; ING2; KLF6; SMARCA5; RBBP4; DNAJC2; SCAND1; PATZ1; BAZ1A; ERG; ELK1; TOB1; MBD2; CNOT6; HOXA10; VGLL4; TAF9; RNF138; PSMC3IP; RBM14; GTF2A2; ELF1; RNF111; IRF7; TLE1; BIRC2; APEX1; VEZF1; REST; NRIP1; BCLAF1; ZBTB11; MED1; TERF2; CRY1; HOXC6; RNF6; SF1; HOXC10; KAT7; ANKRD1; RBM39; RUNX1; BRD3; PSPC1; ADNP; HOXB7; ERBB2; NPM1; SMAD3; NCOA6; AATF; ZBTB1; RB1; TP53; KLF10; SP110; CTBP2; TRIM27; BTG1; RREB1; ATF4; NRBF2; TEAD4; COPS5; MAGED1; MYBL2; GATAD2A; PHF20; SMAD4; ECD; SMAD1; NPAT; HMGB2; PAWR; SAFB2; SMARCC1; MNAT1; STAT3; ZNF443; ZNF217; DEK; TFAM; HSBP1; CBX3; DR1; SSRP1; PUF60; WDHD1; PTRF; BAZ1B; HMGA2; ZNF146; BCOR; YWHAB; ELF5; CCNC; RYBP; RAN; AFF1; PCGF2; GTF2IRD1; EED; ZMYM2; URI1; ZNF302; PRPF6; BATF3; NFE2L1; FOXJ3; E2F3; VDR; SMARCA2; PBX3; SAP30; BRD7; CEBPG; CREB3L1; MED17; HIF1A; BASP1; LMCD1; CTCF; ITGB3BP; SMAD2; BBX; FOSL2; SUZ12; SIM2; CTR9; BMI1; TRIM16; FOXO1; REPIN1; RARA; MAFF; ZBTB38; ELK3; TRIM29; BCL10; ZNF410; POU2AF1; TBL1XR1; SMAD7; TCF12; MYB; ZBTB18; HDAC2; NCOA4; HOXB6; NKX3-1; STAT1; KLF4; DDX5; FOXE1; NR2F2; IRX5; ZFP36L2; WWTR1; ID3; CEBPZ; HTATIP2; THAP11; MAFB; TFAP2C; ENO1; ZNF165; NFATC3; TLE4; AEBP1