Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09446 Pf-431396 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 23 KLF6; DAXX; SMAD3; TRIM29; BRD3; MXD4; RBBP4; NKX3-1; RBPMS; NPAS2; EGR3; FOS; ZNF93; ZNF544; CARHSP1; YBX3; PLAGL1; WWTR1; DACH1; ZNF91; HTATIP2; HOXC6; ZNF586
Down-regulation 62 PTRF; CCDC59; NKX2-1; HMGB2; TP63; NR3C2; C1QBP; BHLHE41; SOX18; HIPK1; FOXA2; HOXB6; HMGA2; VDR; ZBTB16; TCF21; SOX15; ZBED2; BMI1; NR5A2; ID2; IRF4; TCFL5; SOX17; SUB1; SOX13; FOXO1; HEY2; CALR; FOXE1; MECOM; SMAD1; IFI16; TCEA1; NR1H2; BNC2; FOXF2; TCF4; PRDM2; SSX1; FUBP1; HDAC9; ZEB2; ID4; E2F5; TCF7L2; TBX3; ZNF415; SNAI2; BNC1; SATB1; MNDA; MYBL1; ZNF589; WT1; MEIS2; PEG3; ZFPM2; THAP11; SPDEF; ERBB4; MYB