Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09445 Pf-431396 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 85 RELB; DLX2; NFE2L3; HSF1; CAMTA1; HMGA1; FOXA2; ERF; CCNE1; SMAD6; ARID4A; DLX5; HBP1; VGLL4; SMARCB1; HDAC4; CEBPB; ZNF180; ID1; REL; THAP10; PPARG; ZNF184; ZMYND8; POU4F1; ARID4B; KLF5; SATB2; NR1H3; EGR3; HOXA10; ZNF195; ZNF112; NPAS2; AES; NFKB1; HDGF; TDP2; TSC22D1; NAB1; BAZ2B; BCL11A; SOX17; SPI1; ARNT2; LEF1; SPIB; TLE2; ZNF217; RERE; LMCD1; CBFA2T3; POU2AF1; BCL3; MECOM; CERS6; GTF3A; MYB; ZFP36L2; ZNF117; ZSCAN18; HOXB7; ESR1; ID3; EMX2; MEOX2; PLAGL1; TWIST1; TRPS1; ZHX2; RFX5; TLE4; ARID5B; IRF6; E2F5; EHF; TFAP2C; ZNF544; MNDA; DACH1; FOSB; BHLHE41; ZBTB18; ZNF586; WT1
Down-regulation 67 CCNA2; CREB3L2; TFAM; PTRF; ING3; MYCBP; TCERG1; BBX; ZNF148; RBM14; NUP62; CCNT1; CREB1; RBL2; KLF9; ZBTB38; SKI; PIAS1; EDF1; MEF2A; SMAD5; FOXC1; RBPMS; SOX15; WWTR1; VEZF1; CCNC; HNRNPD; HOXA1; MED1; BATF3; HMGB2; MAFB; SOX10; BCL11B; PDLIM1; PURA; BHLHE40; NKX3-1; CRY1; FUBP1; CITED2; KLF2; PITX1; KDM5D; BMI1; NR1D2; ENO1; SSX1; ZNF160; EGR2; ZIC1; IFI16; HLF; HLTF; NR2F2; FLNA; PBX3; TXNIP; CEBPA; THAP11; SATB1; ERBB4; PEG3; SSBP2; NANOG; HOXC6