Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09443 Pf-431396 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 527 EGR1; ZNF350; ZNF268; HLX; SIX5; HBP1; MZF1; LDB1; SOX17; HAND2; TONSL; MXI1; NPAS1; MED12; ZNF205; EHMT2; NR4A2; HIF3A; CD3D; NR4A3; AR; ZNF358; NAB2; RSF1; SPI1; CREG1; ZNF75D; HDAC11; ZNF816; WNT4; ZNF331; TBX6; IRF1; CRTC1; NR2F1; TCEA2; LMX1B; PROP1; FOXO4; HMBOX1; MEF2D; PBX2; EVX1; ELK4; NFIC; RAX; VSX1; MLLT1; SHOX2; ZFHX2; CAMTA2; RBFOX2; THAP10; CDX1; NR4A1; ALX4; NKX2-8; ADRB2; TWIST1; FOXF1; HSF4; E2F4; ZBTB7B; TAF6L; FOXJ1; NKX2-5; DBP; CRX; ZNF611; TGFB1; FEZF2; LHX5; LHX6; ESRRB; DLX5; HDAC9; TBX10; ATF6B; ZNF528; ZNF274; NEUROG1; SETDB1; ZSCAN18; ZNF701; FOXA2; NKX6-1; SUPT7L; CALCOCO1; MYCN; HOXC8; MED25; TGIF1; ZNF623; RBL2; GBX1; FOXP3; SOX1; FOXL2; FOXB1; PHOX2A; MAPK8IP1; OSR2; ONECUT1; NEUROD2; MEIS1; TLX1; FOXC2; ZNF91; REL; ZNF500; PGR; NFIX; NEUROG3; RFX1; RORC; IRF8; HEYL; ZNF544; ZNF345; NR5A1; ASCL3; HOXC5; ARID5A; BARX1; ESR1; ZNF580; MLXIPL; HIC1; ESR2; ARNT; THRA; HNF4G; TLX2; ZNF771; PAX7; SOX2; YAP1; NFAT5; SIN3B; ZBTB43; PRDM8; CEBPE; DLX4; SOX3; KAT2A; HOXB1; ETV7; ZNF180; ZNF468; CBX4; ZFX; HNF1A; ZNF813; HOXD3; ATN1; CDX4; IRF3; KDM5C; CREBL2; ZNF562; TGS1; PBX1; PRDM1; FOXL1; SSBP3; FOXF2; GATA1; ATOH1; TBX21; HOXB5; GBX2; ZBTB7C; EP300; RBPJL; RORB; ZNF432; NEUROD6; ZNF195; SCRT1; SKI; ACTL6B; HOXB8; CDX2; PPP1R13L; BHLHE40; NR5A2; BCL11A; CUX2; TFDP2; MAP3K10; HOXA3; ZNF423; SUPT3H; ERBB4; BRF2; ZNF529; NEUROD4; EMX1; NR2C1; DLX6; FOXD3; PBXIP1; SRCAP; PDX1; ZNF329; SRY; ZNF532; NKX3-2; NCOA3; MYNN; SOX21; LZTR1; TRIM22; TP73; TRIM33; SOX5; TBX5; NACA2; DOT1L; IKZF3; POU4F3; CNOT3; TFAP2A; DDIT3; EMX2; KAT6B; NR1I2; BCL6; ZNF606; OVOL2; LEF1; CBX7; PRDM16; NEUROG2; ZNF117; PAX1; ZNF14; LBX1; ETV2; ZNF22; HDAC5; MECP2; SCAI; EZH1; POU3F3; ZNF10; GSC2; BRWD1; L3MBTL1; TERF1; VPS72; GRIP1; PHF1; TBX4; TULP1; TBX19; IFNB1; GATA6; SOX13; ZNF415; VGLL1; HOXB13; ZKSCAN4; TEF; CDIP1; SOX14; KLF15; NHLH2; CNOT2; DCC; CEBPD; HOXD10; INSR; AES; ZNF721; KLF13; LHX3; AFF3; MAML3; HAND1; KLF1; SKIL; ZNF787; PAXBP1; ZFPM2; ZNF264; EPAS1; LITAF; LHX1; SIX6; ZNF549; CERS6; ZNF442; OVOL1; IKZF1; SOX18; ZNF695; ZNF223; KAT2B; ZNF749; NHLH1; TEAD3; ZBTB3; ZNF224; PKNOX2; ZNF8; RORA; ARID4A; PEX2; BLZF1; MYT1; ZNF160; LIN28A; PRDM9; MAK; TLX3; ZNF407; POU6F2; HOXD12; NR1H3; ZNF225; TXNIP; POU3F4; CSDC2; TBX1; SSX3; ZNF688; TRPS1; ZNF770; AIRE; NR0B1; NR1H4; ZXDC; HES2; ZNF557; ZNF304; MEIS2; ZNF80; ZNF154; ZNF93; ZNF124; ZNF778; ZSCAN31; DMRT1; ZNF536; ZNF682; RHOA; ZNF467; RING1; PITX1; BRDT; VHL; ZNF140; RFX3; MNX1; SSX7; POU4F2; TBR1; ZNF440; NR2E1; ZNF112; ZBTB48; ZNF157; FOXH1; ST18; TLE2; GCM1; ZNF674; SP140L; ZNF41; MYEF2; CALR; STAT4; HDGF; TFDP3; ZNF671; ZNF492; ING4; RARG; HMGA2; ASCL2; PRDM10; TCEA1; ZNF343; ZNF81; GCM2; CARF; PLAGL1; CREM; GRHL2; ZNF155; PAX6; ZNF814; ETV3; UTF1; FOXA1; ZNF573; ZNF667; SREBF1; CBX2; THRB; MDM2; CTNNB1; CREB5; ZNF471; TAF1C; ZBTB44; KLF9; ZNF665; ZNF253; ZNF257; VENTX; ARID1A; MSX1; OLIG2; KLF8; PEG3; FOSL2; ZNF74; PRDM14; ZNF362; POU2F3; SATB2; WWP1; ZBTB16; PRDM5; ZNF44; PRDM2; ZKSCAN8; SPDEF; ZNF132; ZNF654; ZNF551; ASH1L; TDP2; MYRF; PAX4; SALL1; NR1H2; MNDA; EGR3; ARNT2; ZNF493; HESX1; ZIC3; TRIB3; ZNF211; ZNF273; MITF; ZNF587; ZNF135; CHD9; ZNF83; SLC2A4RG; STAT2; ZNF391; MAF; DLX2; ZNF214; ZNF239; ZNF235; GFI1; ZNF134; ID2; POU1F1; TAF1D; SP4; FOSB; HEY1; ZNF141; TCF21; ZNF254; HIPK2; POU5F1B; SALL2; ZNF780B; ZNF43; ATF3; ZNF675; MAFF; ZIM2; ZNF208; JAK2; TFEC; HIC2; HOXB2; CHD2; JARID2; IRF6; SIX3; HOXD1; NKX2-2; ZNF136; MYT1L; CBFA2T3; CRYM; ZNF711; HOXB6; HLF; TCF4; RXRA; TSC22D1; BCL11B; PIR; BCL3; ZNF669; NFATC4; SOHLH2; MYCL; IRX5; TBX2; MECOM; FLI1; E2F2; MEF2C; ZIC1; MAFB; WWTR1; SPIB; ID3; GATA2; ID1; NR1D2; HES1; WT1; DACH1; ZNF586
Down-regulation 170 HOXA5; CCNA2; FHL2; PARP1; UBE2I; ECD; CRK; MBD2; XBP1; TP53; NUP62; USP22; NRIP1; SNW1; GTF2A2; BCLAF1; HNRNPD; ZNF672; SMARCA5; YWHAB; TRIM29; ATF1; RFC1; TBP; VGLL4; MED6; CCNC; CENPF; RBM14; SP110; TBPL1; SMARCE1; BAZ1A; DNAJC2; PAX8; PATZ1; CDK7; SCAND1; FOSL1; CNOT6; HOXA10; CNOT1; SMAD1; MMS19; RBBP4; PUF60; TGFB1I1; ZBTB11; YAF2; ZBTB24; BRCA1; MED27; PTRF; HDAC2; SMAD3; NPM1; RNF111; TLE1; NCOA6; ZNF143; MED1; IRF7; RBPMS; WHSC1; SP100; ZBTB40; BRD3; HOXC6; KAT7; PIAS2; ZNF263; VEZF1; ZNF281; MYBL2; CTR9; RNF138; ELK3; HMGB2; PRPF6; KDM2A; TAF9; RCOR1; ARID4B; TRIM32; RAN; NELFB; KAT8; GABPB1; MAGED1; BCOR; CCDC59; ZBED4; SFPQ; ILF2; PHF20; FOXD1; UBE3A; REST; ASXL1; ING2; SSRP1; SETD3; ORC2; TAF10; DEK; KDM5D; GTF2IRD1; NRBF2; MAX; PSMC3IP; CREB3L1; BRPF1; TRIM16; MNAT1; DAXX; NPAT; BRD7; ITGB3BP; KMT2A; SMAD4; RNF6; ARNTL; EED; PCGF2; EDF1; TBL1X; ZBTB1; ZNF217; HOXB7; SMARCD3; GATAD2A; BATF3; DR1; CITED1; NR2F2; TP63; ZMIZ1; ZNF146; TBL1XR1; HIF1A; RUNX1; CBFB; XRCC6; SERTAD2; TCF12; CBX3; CRY1; BTG1; IFI16; BASP1; SAP30; KLF6; PTTG1; EYA2; HSBP1; SUB1; ERG; LMCD1; DNMT3B; CREB1; STAT1; CEBPZ; TLE4; CTBP2; ZBTB18; FLNA; SOX9; ARID5B; THAP11; PPARG