Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09438 Gsk-1059615 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 182 HDAC6; MZF1; MNAT1; GON4L; EGR1; NAB2; DBP; KLF13; FOXG1; FOXO4; ZNF444; ZNF205; SETDB1; CNOT2; RBFOX2; TCEA2; SUPT6H; BPTF; PCGF1; RSF1; CALCOCO1; MED12; TBX2; FOXJ1; ZNF195; HBP1; HSF1; ZNF268; IRF3; ZNF212; DLX5; CAMTA2; MED15; CBFA2T2; TLE2; HOXD11; NFIC; ING4; RING1; NR2E1; NR2F1; SSBP3; PIAS4; MTA1; MLXIPL; ZNF629; CEBPE; HOXD10; ZNF45; HOXC11; ARID1A; ZFHX3; HOXB5; ZSCAN32; TGFB1; ZNF133; TCF3; MED25; AES; SIN3B; ELF3; HOXA11; CIC; ATN1; PROP1; POU2AF1; MED24; PRDM1; HDAC7; SOX4; SIX1; ZNF34; HOXB2; TRIB3; MAZ; HSF4; ZNF180; ZNF75D; ZNF500; SRCAP; DLX4; EZH1; EZH2; NR2C1; SP2; CBX4; DDIT3; GATA1; ZNF580; MECP2; KDM5C; HMBOX1; HES1; CARM1; DEAF1; ZNF3; TWIST1; ZNF223; CBX7; MEOX2; BATF3; CNOT3; ZNF835; EP300; CD3D; HDAC4; ZNF112; HMG20B; ARNT2; ATF7IP; TFCP2; CLOCK; ZNF227; HEY1; CERS4; PCGF3; HLX; STAT4; MEIS2; MEIS1; MAFG; PHIP; ZNF274; TBX21; OVOL2; ZNF623; LHX3; HOXD1; ZNF688; HOXC4; HIPK2; ZNF671; HDAC5; HDAC9; MKL2; VPS72; ETV5; GFI1; SIX6; FEZF2; RARG; MED14; CHD9; PAX5; PPARD; TAL1; ZNF211; FOXF2; FOXD1; PAX6; INSR; IRF8; NCOR2; PRDM2; ZFP36L1; CEBPB; TRIM28; LPIN2; ATF4; ST18; ID1; SOX9; EYA2; TFAP2A; PRDM14; CBFA2T3; YBX3; TRPS1; SIX3; KLF11; SALL1; EGR2; AHR; ZNF711; HOXB7; MDM2; TOX; ZNF415; SPDEF; ESR1; MNDA; IKBKAP
Down-regulation 107 ATF6; XBP1; NFKBIA; ATF1; GTF2A2; PAX8; CCNA2; FOSL2; TRIM29; GATAD2A; BBX; TRIM16; ING3; NRIP1; TFDP1; MYCBP; MYCN; TSC22D2; HIVEP2; PTRF; NFIL3; ELF1; PIAS2; ECD; YWHAB; DNMT3B; SFPQ; MITF; TFAM; NFKB1; HIPK3; ZNF672; BCLAF1; YAP1; SMARCA2; ABL1; PURA; MEOX1; CHD1; WWC1; TAF1D; CREB5; CBFB; EDF1; BTAF1; HSBP1; SMARCA5; EHF; SMAD3; TOX3; FOSL1; HNRNPD; RBBP4; ENO1; ELK3; MBD2; LMCD1; KLF4; TEAD1; ING2; ADNP2; SOX10; ELF5; PBX3; ZNF165; VEZF1; CRY1; MAGED1; SAP30; MAF; TXNIP; KLF6; KLF2; GATA6; CREB1; NR2F6; STAT1; CHD7; RBPMS; ZBTB18; YBX1; KLF9; NCOA4; RAN; SMAD2; TRIM32; ZNF302; BMI1; PEG3; ZNF91; ZBTB38; WWTR1; NCOA1; HOXA1; LIN28A; ZSCAN18; ETS2; ID4; SNAI2; HIRA; ZNF652; TBX3; TCF4; MYB; DACH1; NANOG; ZNF586