Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09437 Gsk-1059615 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 298 ETV1; KDM5B; EGR1; CNOT2; JUP; MZF1; ZNF528; MAFG; ELF3; KMT2D; RSF1; HDAC6; TCEA2; EP400; HMGA1; ZNF384; RBL1; STAT5B; ZNF268; CAMTA2; MLXIP; BPTF; SHOX2; CD3D; NR2F1; OSR2; ZNF7; EZH1; CDK7; ZNF16; ZNF282; WWP1; HIVEP3; PLAG1; GON4L; ZBTB16; MTA1; HOXB3; ST18; TRIM24; ETV7; ZNF813; PLAGL1; TAF4; FOXL2; ZNF180; SIRT7; TLE2; BRF2; ZNF623; CTNNB1; ZNF212; ZNF205; SOX4; AES; INSR; SOX17; ZNF701; NFE2; BRCA1; MED12; ZNF274; MED24; HDAC4; SNAI2; TERF1; AFF2; CRTC1; NCOA2; ZNF473; SSX1; ZNF3; HOXD1; TBX21; SIN3B; WNT4; NR5A2; BLZF1; ZNF337; ZNF107; EHMT2; HMG20B; ZNF227; DMRT1; E4F1; RHOA; ZNF692; MDM2; PIAS4; KLF13; ZIC1; TWIST1; KAT7; KDM5D; NKX2-5; DBP; PRDM1; BNC2; NKX3-2; IRF3; SAFB; ZNF787; EZH2; CBFA2T2; EBF2; NFX1; NR0B1; SOX13; ZNF75D; ZNF816; RBPJ; TRIM28; GATA1; NR2C1; ZNF350; ZNF500; JARID2; SATB1; TRRAP; RING1; DDIT3; NR1H3; TAF7L; GLI3; HIF3A; HMGA2; NKX2-1; ZNF34; ZNF835; LZTS1; TAL1; SOX2; MED16; ZNF536; ZFP37; ADNP; ZNF696; GFI1B; HCFC1; THAP1; TP63; ASH2L; SIX2; MYEF2; ZMYND8; ETV4; ATF4; NCOA6; KAT5; NCOA3; SOX10; IRF1; FOS; CARF; YEATS4; ZKSCAN1; ZNF557; ZNF286A; STAT4; MYT1; CBX7; ZBTB3; HMBOX1; ZNF225; PGR; ZSCAN9; PEG3; EYA2; EP300; PAX9; DPF2; ZNF492; ZNF552; BATF3; BACH2; SOX18; FEZF2; ZIC3; TRPS1; ZFY; SIAH2; CARM1; FOXG1; PITX1; TGIF1; SIX6; ALX1; ZBTB44; IKZF2; EGR3; PCGF3; ZNF695; TXNIP; BARX1; ZNF611; HMGB3; ZNF749; MEIS2; TRIM22; SP2; MDM4; PPARD; CHD2; KLF1; ZNF195; ZNF74; ZFPM2; ZNF407; NHLH2; L3MBTL1; HLX; RUNX3; TBX1; RORA; SCAI; ZBED2; ARNTL2; KAT2B; FOXA2; PAX4; ETV5; KAT6A; LPIN2; TFDP2; FOXA1; ZNF415; AEBP1; TCFL5; PKNOX2; ZNF329; ZNF493; ZKSCAN4; PHIP; ZNF532; ZNF721; ZNF224; E2F2; ZNF83; ZNF544; SMARCD3; MEOX2; ZNF654; POU1F1; KLF5; ZKSCAN8; GLI2; ZNF175; ZNF214; HOXB2; EN2; ZNF132; IRF8; ZNF426; FOXC1; NFAT5; WT1; CEBPB; AFF1; PRDM14; E2F8; ZNF85; ZNF257; ZNF43; ZNF160; BCL3; ZNF468; IKBKAP; PIR; ZNF141; DNMT3B; JAK2; CERS6; TFAP2C; TCF21; ZNF44; IL16; NEUROD1; PRDM2; FOXD1; YBX3; TBL1X; BHLHE41; HLF; CBFA2T3; NPAS2; ADRB2; KLF11; GATA6; ZNF551; FLI1; SIX3; PBX1; MNDA; SPDEF; ZNF665; ZNF264; ABL1; SSBP2
Down-regulation 132 LOXL2; CCNH; BASP1; MYCBP; SUMO1; WWC1; ERF; CCNA2; TSC22D2; HDAC3; CBFB; CNBP; BHLHE40; NRIP1; WDR77; NFKBIA; TFAM; BBX; PIAS2; ZMYM2; MED27; HNRNPD; CBX3; TFDP1; ZNF148; ID3; MBD2; SMAD3; TBP; CHD1; RBBP7; ECD; ZNF593; SIM2; RFX5; BCLAF1; PAX8; MNAT1; BIRC2; RNF6; ING2; SFPQ; CCNC; PMS1; BMI1; EMX2; GCFC2; SMARCA5; HOXB9; SAP30; SETD3; ARID5B; ZNF32; CTBP2; ZFP36L2; DMTF1; ZBTB18; ID2; DR1; TAF7; STAT6; TBPL1; YAF2; MYBL2; DACH1; NFATC4; DNAJC1; CRY1; BRD3; SF1; NPM1; ZHX2; CREBZF; ENY2; CREB3; BAZ1A; CEBPG; TOB1; BRD7; GATAD2A; ZBTB11; RNF138; SMAD4; GTF3A; EHF; HMGB1; KAT8; NFE2L1; COPS2; RARA; RYBP; HIF1A; ELF1; CREB1; ZNF302; HMGB2; MYCN; ZBTB38; MEF2A; MXD1; PBX3; NPAT; E2F5; THAP11; TGIF2; STAT1; ELK3; TGFB1; KLF9; HIRA; MXI1; HOXC6; TOX3; CALR; HOXB7; CHD7; MAGED1; LMCD1; ESRRG; KLF2; ZFP36L1; NR2F2; FUBP1; ATF3; MSX1; ZEB2; GATA3; ZNF165; SOX9; TLE4; ZNF423; TBX2