Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09436 Barasertib-hqpa GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 37 E2F2; SFPQ; CCNC; ZNF468; HMGA1; POU4F1; ZNF586; PFDN5; TBPL1; BCLAF1; ZSCAN18; TOB1; ZNF304; ZFP36L2; CREBZF; SMAD2; ID2; CEBPB; TBL1XR1; DLX5; KLF10; PRKDC; EHF; FOXO1; ESR1; ZNF551; GATA6; LPIN2; TAL1; BTG1; HOXC6; TSC22D1; ZNF91; SOX9; FLNA; TOX3; NFATC3
Down-regulation 47 NR2F1; BCL6; SHOX2; RBFOX2; KLF7; LZTR1; MECOM; CREB1; FOSL2; NR4A1; KDM5D; CEBPD; MEIS2; CREM; AHR; PAX6; SOX2; HLX; RFX5; NR4A3; RBPMS; EGR2; EYA1; HEY1; BNC2; INSR; ZFP36L1; ZNF710; SALL2; TCF7L1; HMGB3; CEBPA; SPDEF; SOX11; HIRA; ZFPM2; WT1; MEIS1; FOSB; HIC2; PBX3; NR2F2; TCF4; MEF2C; GATA2; SSBP2; PPARG