Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09434 Barasertib-hqpa GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 25 TBX2; BATF; SMAD3; HOXB7; CHD1; HOXB6; DDIT3; MAFB; PBRM1; ZKSCAN1; BRD8; JARID2; HMGB1; ZFP36L1; ZNF587; BATF3; CBX3; NKX3-1; PIR; NR1D2; NR2F2; HLTF; NFATC3; HOXC6; ESR1
Down-regulation 74 HOXB13; ZNF536; ZNF133; SMAD7; CCNE1; BCL11A; ZFP36L2; INSM1; CBFB; HEY1; YBX1; HDAC9; RBFOX2; SOX11; NKX2-1; NFATC1; KLF4; PHOX2B; TAF9B; PIAS1; DLX2; TBX3; EHF; PAX5; BACH2; ZEB1; SMARCA1; MYCN; MAF; ISL1; ZNF532; FOXA2; TLE4; SHOX2; HOXD1; SOX17; ZNF711; PLAG1; RFX5; ZKSCAN7; ST18; IFI16; SUB1; ZNF512B; ZSCAN31; POU2AF1; CBFA2T3; REL; BAZ2B; SIX3; EMX2; SMAD1; E2F5; HIRA; BNC1; IRF8; MEIS2; TCF4; ASCL1; NR1H2; ZNF652; ZNF165; TFAP2C; ZBED2; TRPS1; THAP11; EN1; IRF6; TOX; MYB; ID1; ADRB2; NFKB2; PPARG