Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09433 Barasertib-hqpa GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 32 CEBPA; NCOA3; LEF1; TAF7; HOXB7; NKX3-1; SP140L; CEBPG; KAT6B; CTBP1; BRD3; SMARCA2; STAT6; HOXB6; TRIM16; MXI1; HOXC6; HOXC10; CRY1; BRD8; TRIP6; RFX5; PTTG1; ZNF302; LPIN2; ZFPM2; BHLHE41; ZBTB38; MSX1; GATA6; THAP11; IKBKAP
Down-regulation 63 HMBOX1; HMGB3; CAMTA2; MKL2; INSM1; CREB1; HMX1; SMAD7; KLF7; ACTL6B; SRCAP; RCOR3; SNAI2; RARA; ATOH1; AR; CRYM; PDLIM1; HDAC9; NR2F6; ZBTB20; HLX; ACTL6A; SIX3; PAX5; EGR4; KLF10; TRPS1; PLAGL1; ZNF224; MYCL; IRX5; EYA1; HOXD1; SMARCA1; VPS72; PAX6; CITED2; CBFA2T3; ZNF160; JUP; SOX11; ZNF611; ETS2; ZNF721; KLF9; FOXG1; SATB1; ASCL1; ID1; LITAF; ZSCAN18; NEUROD1; IRF6; ZBED2; TBX3; ZNF91; FOSB; TCF4; HES1; SSBP2; DACH1; ERBB4