Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09432 Barasertib-hqpa GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 49 NPM1; HOXB7; GABPB1; RREB1; LEF1; STAT6; CCDC59; AATF; ZBTB11; PQBP1; NR2C1; DMTF1; HOXB6; IRF4; HOXC10; BRD8; DDIT3; HOXA10; BAZ1A; MEOX2; TRIM22; MXI1; SALL1; TGIF1; JARID2; ZNF516; TRIM32; PCGF2; KAT6A; CTBP2; ID2; ZBTB18; LPIN2; TRIP6; BRD2; HOXC6; PTTG1; TCF12; HTATIP2; FOXO1; RORA; ZFP36L1; NR2F2; MAGED1; ZEB2; TXNIP; IKBKAP; AFF1; MSX1
Down-regulation 63 WIZ; NRIP1; PHOX2A; SMARCB1; SREBF2; ATN1; FOSL1; PHOX2B; RBFOX2; FEV; CBFA2T2; HOXB13; TFAP2A; PPP1R13L; INSM1; TRIM29; MAF; ZEB1; KLF7; TAF9B; BMI1; NPAS2; FOSB; ARID3B; TRPS1; BCL11A; CITED2; VPS72; BHLHE40; JUNB; HOXD1; PITX1; SNAI2; JUND; HEY1; HIPK2; ZNF264; CALR; ETS2; SMAD1; FOXF1; JUP; PAX6; THAP11; SOX9; ATF3; ID1; TOX; FOXF2; TFEC; NR1H2; IRF6; E2F5; SIX3; LITAF; KLF4; ZNF665; EN1; SSBP2; WT1; DACH1; TOX3; PPARG