Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09431 Barasertib-hqpa GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 25 FOXC1; WWC1; NPAS2; ELK3; RBBP4; MAFB; SMAD6; SOX9; ETV4; VEZF1; MTDH; BATF3; FOS; TRIP6; HOXC10; BRD8; ZBTB38; TSC22D1; ETS2; TOB1; AFF1; HLTF; ZBTB18; KDM5D; HOXC6
Down-regulation 109 NAB2; SETDB1; ZNF281; SOX11; BACH2; ILF2; MEIS2; HMBOX1; CREB1; MKL1; HIRA; ZBTB20; ZNF160; AFF2; THAP7; KLF11; ZNF611; NR2F6; SP140L; POU2F1; PKNOX2; BAZ1A; KDM4C; OVOL2; ZFPM2; YBX1; POLR3C; ZFP36L1; FOXO1; PEG3; NR4A3; ZNF74; BCL6; CBFA2T3; IRF1; EGR2; SOX5; SPIB; FOXA1; NR4A2; BACH1; NR0B2; HIVEP1; NFATC3; NR1H4; ZNF721; PAX5; AEBP1; INSM1; PAX6; ZNF500; GATA6; ZHX2; YEATS2; TGIF2; KMT2A; ZNF10; ZMYND8; CHD9; ZNF107; MYBL1; ZNF136; ZNF224; CHD7; ZNF83; SOX2; ZNF232; MDM4; HDAC9; TCF21; PITX1; HEY2; HIC2; PRRX1; JUND; ZNF331; EYA2; ZNF93; SNAI2; BCL11A; NEUROD1; OLIG2; FOXG1; THAP11; ARNT2; ZNF273; MECOM; ZIC1; KAT2B; ZNF43; ZNF264; OSR2; BRD4; ARID5B; TRIB3; TRPS1; NKX2-2; MEIS1; KLF9; ZEB2; SALL2; PBX1; IRF6; ZBED2; SPDEF; ZNF665; SATB1; WT1; SSBP2