Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09430 Vemurafenib GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 110 TBX2; MEF2C; PMS1; CHD1; TWIST1; HEY2; MKL2; FOXO1; RBBP8; ZBTB16; RARB; RREB1; ZNF292; CEBPZ; SMAD3; RERE; MAFF; ZBED1; ADNP; UBE2B; CHD9; FOSL2; TBL1XR1; RCOR3; TOX3; PRRX1; MLLT10; EGR3; HMGB3; KLF7; ILF2; EGR2; ITGB3BP; FOXK2; ZNF217; TRIM22; ZNF131; POLR3C; ZNF304; PSMC3; ZNF124; HOXB6; TP63; ZNF688; SOX5; NR0B2; GATA6; ZNF587; ZNF611; ZNF654; ZMIZ1; NR4A2; TXNIP; SAP30; LITAF; SMARCD3; ZNF551; ZNF430; ZEB1; PRPF6; IRF7; MYF6; ARNT2; ZNF586; ZNF426; ZNF606; NR1H3; ZNF589; ZFPM2; ZNF665; BTG1; ZBTB44; ZBTB20; BNC2; E2F8; ERBB4; ZNF160; SPDEF; ZEB2; ZNF711; KAT2B; ZNF273; HIC2; ZNF141; CEBPA; KLF11; TRIB3; MEIS2; MDM2; OSR2; INSR; IRF4; PBX1; HOXB2; TCF21; ZBED2; KLF3; ZNF331; MECOM; ZNF264; CUX2; ARID5B; LEF1; TCF4; PEG3; PBX3; TFAP2C; WT1; IRF6; NFATC3
Down-regulation 55 MED21; UBP1; ELF5; MSC; RYBP; CCNE1; RFXANK; ORC2; DNMT3B; CRY1; PURA; CBFB; BCL11B; BAZ1B; JUND; ARNTL; INSM1; JARID2; MXD4; CUX1; TRIM29; KAT5; MBD2; BBX; USF2; TADA3; JUNB; MAZ; SATB2; HDAC1; CREB1; YWHAB; NKX2-2; BAZ1A; MAFB; SCAND1; BCL3; BAZ2B; FOXC1; HTATIP2; MEIS1; RUNX3; SOX11; EMX2; GATA3; FOSB; NKX3-1; TSC22D1; HLTF; FOXG1; HOXC6; HEY1; THAP11; PPARG; NR3C1