Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09428	Vemurafenib	GSE70138	HA1E	Human	24h	0.37uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	NFKBIB; IKZF1; TSG101; SIX2; PSPC1; BATF; MED4; MNAT1; IRF4; SP110; SMAD6; NKX2-1; STAT6; RBBP8; MED6; NR3C1; GCFC2; TCF7L1; RNF6; HMG20A; POU2AF1; HIPK3; SIAH2; TEAD1; PAX5; PCGF2; PLAG1; HMGA1; NFAT5; ZBTB11; IRF2; ASXL1; MEOX1; TRIM32; NFATC1; GATA2; SMARCD3; KDM5D; NCOA2; ID2; SMARCA2; FOXD1; GTF3A; MBD2; HIPK1; HMGN3; BCOR; NAB1; MEF2A; SSX1; E2F5; LEF1; ELF1; SOX11; GTF2I; NCOA4; ZNF512B; ZBED2; ELK3; SERTAD2; BAZ1A; PBX3; ZEB2; TBL1X; ING2; TFCP2; SMARCA1; PBXIP1; LPIN2; ZMYM2; ZBED1; VDR; HOXB2; ELF5; STAT4; FOXC1; ZNF124; PLAGL1; SMAD7; TRIM22; NR2F2; SPIB; TXNIP; LITAF; ZNF217; CREB1; RBPJ; ESR1; SOHLH2; MYB; ID3; ZBTB38; TLE4; AEBP1; ID1; WT1; PEG3
Down-regulation	85	WIZ; INSM1; HOXB13; SIN3B; ZNF384; ZNF552; RBFOX2; PTRF; DNAJC1; ZBTB20; MYRF; NR4A1; MED21; MEIS1; HMGXB4; RNF14; BRD7; KMT2A; TEAD3; FOSL2; ZNF189; NKX3-1; FOXF1; TBX3; CBFA2T2; WWC1; ST18; MAFF; TLE2; EHF; FOXG1; TULP3; TGFB1I1; KLF5; IRX4; CREBZF; ATN1; CBX6; PSMC3; RBM39; NR2F6; ARNTL2; EDF1; RXRG; FLNA; ATF3; FOXA1; NR2E1; NR4A2; LZTS1; JUND; NLK; BIRC2; CBX4; JUNB; OLIG2; TDP2; DDX5; TBL1XR1; PHIP; ACTL6A; ZNF652; CREM; PITX1; SMAD1; SOX13; NKX2-2; ERG; ZNF532; HDAC1; CBFA2T3; ELF3; TCF21; ZNF467; MECOM; CUX2; TRPS1; ZNF83; THAP11; FOSB; NEUROD1; HES1; NANOG; PPARG; ZNF586