Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09427 Vemurafenib GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 70 IKZF1; SIX2; SP110; RRN3; TSG101; PSPC1; CDYL; HOXC10; MKL2; SMAD6; TERF2; MEOX1; HOXB2; LITAF; SIX1; POU5F1B; ZEB2; SP140L; BRD3; ZNF32; MLX; STAT4; PEG3; EGR3; CREG1; RAN; ZNF536; DEK; HOXC4; DLX2; PRRX1; ZNF654; PBX3; NFAT5; PHF20; ELF5; LPIN2; PITX2; INSR; ID2; HHEX; PLAGL1; GFI1; ZBTB16; HIC2; TGIF2; LIN28A; ZNF124; JAK2; MAFB; BRD8; HMGB3; ARNT2; CALR; ZHX2; TOX3; ZNF160; YBX3; TRPS1; ZIC1; TRIB3; ZNF423; EYA1; MNDA; NANOG; TFEC; PBX1; MSX1; HOXC6; NFATC3
Down-regulation 48 PIAS2; CHD1; TSC22D2; KLF6; SUB1; TLE2; BCLAF1; RBPMS; TSC22D1; NAB1; RNF14; WWC1; RELA; TGFB1; RBM14; NLK; MEIS1; CTNNB1; ACTL6A; KMT2A; KLF10; MBD2; ETS2; ZNF329; CREBZF; ZBTB20; PAWR; SP3; FOSB; ELK3; AEBP1; JUND; JUNB; ZEB1; BASP1; CRY1; SMAD2; BHLHE41; CREB1; ZNF711; LEF1; MEIS2; NR4A2; MECOM; MYB; ATF3; HES1; ZNF586