Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09426	Vemurafenib	GSE70138	HA1E	Human	24h	3.33uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	143	NFKBIB; BATF; IKZF1; FOXN3; TAF4; LPIN2; IRF7; ELK3; SIAH2; MAML1; TBX2; CREB3L1; RBBP8; AHR; RCOR1; POU2F2; ZFHX3; MEF2C; ELF2; RBBP5; NR3C1; TFCP2; RSF1; SSX1; ZBTB11; PURA; SETD2; ARHGAP35; ZNF593; KLF6; GATA4; NR2F1; MAX; REL; NAB1; ZNF267; ZMIZ2; UBE2B; TCF12; ZNF354A; ZFX; TSG101; ZBTB39; LMCD1; NKX2-1; BCL6; ARID4A; ID3; ELF5; ZNF212; VDR; DR1; SMARCC2; PKNOX2; YAF2; ELF1; IFI16; LEF1; MED6; SSBP2; ASXL1; SMAD7; CTR9; TAF1A; MECOM; KAT2B; GATA6; TBX21; LHX1; GATA2; ZNF22; TTF2; STAT2; ZNF32; TRIM22; TAF11; NCOA1; SERTAD2; CNOT2; HMG20A; BPTF; PLAGL2; RBL2; IRF9; TAF1D; ZBTB18; ZNF165; CCDC59; HCFC2; CREG1; FOXJ3; PBX1; NCOA2; MLLT10; HIPK3; BCOR; PGR; IRF8; ZNF177; PAX5; ETS2; MDM4; ZNF107; NR1H3; MAFB; JAK2; TOX; SMARCA2; SATB1; IRF4; NCOR2; MEF2A; FOXO1; DDIT3; BAZ2B; ZFPM2; POU2F1; EGR4; ZNF516; NR0B1; SPIB; POU2AF1; MAGED1; ZNF423; ZNF124; CBFA2T3; ETV5; INSR; E2F5; HOXC10; ID1; BRD8; IRX5; ZEB2; CEBPZ; TCF4; CTBP2; TCF7L2; ZFP36L1; SOHLH2; ZNF331; NFATC3; WT1
Down-regulation	106	HMG20B; PUF60; HSF1; HOXB13; INSM1; BCLAF1; HBP1; MMS19; RBM39; KLF7; CRTC1; C1QBP; WIZ; THAP4; CNBP; RFXANK; CITED2; SOX10; PIAS1; MAF; PTRF; BHLHE41; EMX2; CBFA2T2; SREBF1; AR; HOXD11; MAFF; CREB5; SND1; FOXG1; HDGF; HHEX; TDP2; ILF2; SSBP3; WWTR1; YBX3; TRIM29; NFIC; ETV4; ZNF189; JUND; TULP3; HOXD1; PITX1; BNC2; CALR; NPAS2; MED24; KDM5D; HOXD13; PPARGC1A; NRIP1; ZFHX4; BHLHE40; GTF2IRD1; CREB1; AES; JUNB; MITF; TULP4; CREBL2; COPS2; ISL1; YBX1; ZIC1; SHOX2; TRPS1; NR2E1; KLF9; DLX2; LZTS1; NKX3-1; ZNF394; RBPMS; HOXA7; NR2F6; ZNF93; PAX6; CTNNB1; CRYM; HSBP1; ZNF146; ENO1; SATB2; MEIS1; NFIB; TCF7L1; BBX; SOX17; FOXA1; ZNF544; THAP11; BRD4; NR1H2; NR4A2; FLNA; ATF3; TBX3; SOX11; LITAF; EN1; ST18; NANOG; PPARG