Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09425 Vemurafenib GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 276 EGR1; ZFHX3; NFKBIB; THAP10; EP400; NR2C1; ZNF24; RSF1; SALL2; ZNF444; ZNF268; TRIM33; MEOX1; ZNF282; SMAD6; ZNF133; IKZF1; PAXBP1; VAX2; BRF2; ZNF516; AIP; ZIC1; SMARCB1; AFF2; WNT4; ZBTB16; CBFA2T3; NFATC1; KAT6B; HHEX; E4F1; FOXL2; ZNF219; TRIB3; NKX2-1; TGIF2; SUPT7L; PRDM12; TAF5; MLXIP; ST18; ZNF536; GBX2; TBL1X; PHF8; HOXA11; GRHL2; SHOX; CXXC1; ARHGAP35; ZNF552; SETDB1; HIF3A; ZNF75D; CEBPE; ZNF22; MED23; APEX1; MZF1; GFI1; MED12; GON4L; RBBP4; CUX1; ZSCAN31; NEUROG1; TRRAP; NFE2L3; JAK2; PRDM16; TEAD3; MYNN; HDAC4; SOX1; CALCOCO1; PGR; MLLT1; TGFB1I1; ZNF112; ZNF32; UBE2L3; ZNF580; SCRT1; TEAD4; BACH2; SOX12; SOX17; TRAK1; ZNF467; BRWD1; DBP; ZKSCAN4; TLE2; TULP1; GLI2; HCFC1; TULP3; ETV6; ZNF195; ARID1A; ARRB1; MAK; FOXE1; MECP2; ATN1; ZNF248; ARNT2; SMARCD3; HOXC4; ZNF232; FOXN3; BRCA1; CSDC2; ZFPM2; MECOM; ZSCAN9; DLX2; GATA3; BATF; MXD4; OSR2; ONECUT2; HOXB6; ZKSCAN7; ZHX2; BRIP1; CRYM; CERS4; ZNF350; FOXO1; CAMTA1; ZNF235; SSBP3; CDIP1; ELF5; NHLH2; ZNF354A; CREBL2; NEUROG2; TLX3; FOXF2; NCOA3; ZNF155; TTF2; NRL; CBX6; NKX3-2; SRY; CITED1; CHD4; ZNF227; ZNF223; ZNF180; HEY1; ESR1; SPIB; ING4; ZIC3; SOX18; HOXA10; ZBTB3; ZNF215; CNOT3; STAT6; SOX13; MEIS2; ZNF423; ZNF225; MYRF; TRPS1; SP140L; SIX6; PRDM9; FOXA1; TRIM22; ZNF532; ZNF33B; ARID4B; BRDT; REPIN1; CTBP1; ASH2L; CHD2; MXI1; NR1I2; THRA; ZNF304; DMTF1; RBPMS; PBX1; ZNF589; TFCP2; TAF4B; NFAT5; MYT1; THRB; INSR; UTF1; GATA6; CREB3L2; ZNF778; VENTX; HEY2; HIPK2; TCF7L1; CEBPD; HESX1; LITAF; POU1F1; CBX4; FEZF2; ZNF415; NANOG; ZNF257; PRDM2; HDAC9; BNC2; NR1H2; KMT2A; PIR; ZNF239; NR2F1; EN2; PRMT2; PEG3; SOX3; POU2F1; ZNF334; CTBP2; ZNF132; ZNF264; BAZ2B; ZNF165; SOX9; SPDEF; SOX2; ZNF492; ATF4; FHL5; ZNF652; REL; MEF2C; LIN28A; E2F2; TBX2; FOSB; HOXC10; NR1H4; PAX6; MYT1L; ERBB4; SIX3; ZBTB44; NR5A2; SALL1; TRIM28; E2F5; BCL3; LMCD1; AEBP1; KLF3; ELF3; SOHLH2; HOXB2; ESRRG; THAP11; TCF21; IRF6; HIRA; ADRB2; NEUROD1; TFAP2C; MYB; GATA2; ZBTB18
Down-regulation 70 MYCBP; KLF10; STAT3; YWHAB; RCOR1; TSC22D2; TLE1; GATAD2A; RHOA; RBM14; REST; CNBP; EDF1; SMAD3; SFPQ; SATB2; PRRX2; LEF1; ARNTL2; ENO1; RLF; FOXJ3; RNF6; KLF5; ZBTB11; ID2; NELFB; HSBP1; YBX1; NAB1; BHLHE40; RNF14; MAZ; ELK3; TAF10; ALX1; TOB1; STAT1; VEZF1; ERBB2; BCLAF1; NEDD8; BCL11B; ZMIZ1; CHD9; CBFB; NKX2-2; MED1; ZBTB1; PTTG1; ZNF146; BMI1; MEF2A; RAN; MAGED1; ING2; CARHSP1; BATF3; CREB1; BASP1; ZNF217; FLNA; BBX; HMGN3; ZBTB38; RFX5; CITED2; AFF1; NFATC3; ID3