Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09406	Mitoxantrone	GSE70138	HA1E	Human	24h	10uM	EID0036

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	CARHSP1; NKX2-5; NR1I2; NR5A2; CTNNB1; MXD1; ARL2BP; MNX1; TDRD3; PRMT2; SAP18; ZEB1; ZFX; MEOX2; CERS6; GCFC2; NKX2-2; TAF7L; PA2G4; ZNF180; SIX6; HNF4A; ZNF205; CDX1; AEBP1; MLXIPL; MLXIP; TULP4; RNF14; CNBP; ZNF136; TCF7; INSM1; BCL11B; CDX2; PSMD9; RBPMS; KAT2B; FOSB; PEX2; ZNF721; KLF4; MXD4; ZNF224; AES; ZNF667; GATA1; ZNF329; WDR77; HOXD1; TAL1; ZNF695; ZMYND8; ZNF688; MYCBP; NCOA6; FOXJ1; HMGN3; ZNF226; SOX18; HLX; MAZ; HMGA1; MTA1; MECOM; PURA; CBX6; CREBL2; HLF; EHF; ZNF671; ZNF701; TRIM24; TCEB2; HOXD3; NR3C2; ZNF131; CD3D; TXNIP; ATOH1; ZNF606; TCEA1; KDM5C; SOX17; ZNF160; TBX1; ZSCAN18; ZSCAN31; DACH1; EN1; VGLL1; YWHAB; LITAF; ISL1; DLX5; KLF5; MBD2; MSX1; SIX3; NFE2L2; PAX6; CREM; KLF13; DMTF1; ZNF91; MYCN; ZNF117; HMBOX1; SOX11; FOS; NRIP1; NANOG; SUB1; RFX5; PEG3; GLI2; BCL11A; ATF3; ESR1; STAT1; IRF6
Down-regulation	136	NFKBIA; MYC; NFIL3; XBP1; FOSL1; CDK7; RNF111; NUP62; KLF10; PATZ1; TSG101; BRD3; TBP; CCNA2; MGA; CEBPZ; RLF; APEX1; TGIF1; HMGXB4; BHLHE40; YEATS2; ZNF292; HMGB3; ADNP; RNF4; RERE; TBPL1; HMGB2; ARID4B; MED17; VEZF1; HOXA5; AGO2; ABL1; ZBTB1; TBL1XR1; TRIM32; HOXA11; SMAD7; ZNF16; FUBP1; CTBP2; BCL10; CCNE1; ZNF7; FOXC1; FOXO3; FOXK2; NKRF; VGLL4; RCOR1; ZNF133; CEBPB; ZNF337; E2F3; ZBTB16; EGR3; TRAK1; GTF2IRD1; ZNF217; DEK; SMARCD3; FOSL2; BTG1; WWTR1; FOXJ3; NCOA4; DDIT3; ZNF267; HMG20A; ZBTB18; PDLIM1; EED; ZNF12; HOXA10; MAGED1; BLM; SERTAD2; SMAD3; PCGF2; SAP30; PHF20; PPARGC1A; USP22; MTF2; TAF1D; CITED1; ELF5; AFF1; TRIM16; BRD8; NRBF2; CREB3L1; EZH2; CDYL; SIX1; BHLHE41; PCGF3; TCF7L1; FOXO1; NFIB; PUF60; TCF7L2; SOX9; TLE1; ZNF22; HOXB6; BAZ1A; SUV39H1; IRF4; MXI1; HOXB2; CHD7; ID3; JARID2; MYBL1; CTR9; ASCL1; TRIM29; KDM5D; BASP1; CREB1; TOB1; ZFPM2; ID4; SMAD1; NR2F6; ZIC1; DAXX; ID1; ETS1; NKX3-1; NR3C1; ZNF589; EGR2