Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09368	Osimertinib	GSE70138	HA1E	Human	24h	0.04uM	EID0036

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	ZNF611; ZNF160; EPAS1; MYT1L; HMGB3; NCOA3; ERBB4; ACTL6B; ZNF721; CREBL2; TAL1; ZNF665; GATA2; PSMC3; FOXA2; ZNF688; SOHLH2; NHLH1; PRRX1; ZNF75D; ZNF44; ZNF536; NKX2-1; HMX1; SPDEF; ATF5; CRYM; HMBOX1; KLF13; ZNF124; AIRE; SATB1; FOXF1; ZNF606; VPS72; KLF5; NR0B2; NR4A2; TCF7; MKL2; PROX1; TFAP2C; OSR2; NANOG; HHEX; CCNH; LYL1; ZNF117; ST18; HLX; DACH1; KAT6B; ZBTB16; KLF7; PRDM14; ZNF232; BCL11A; AEBP1; INSR; SSBP2; ASCL1; MYRF; HOXD1; ESR1; ZNF91; TXNIP; MEIS2; TRIB3; TCFL5; IRF6
Down-regulation	54	XBP1; PUF60; CCNE1; PCGF2; HMGB2; MSX1; ZNF146; RCOR1; TAF11; MTDH; TFDP1; TBL1XR1; HNRNPD; KLF2; REPIN1; ANKRD1; TCF4; CRY1; LMCD1; BHLHE41; TRIP6; FLNA; PIAS3; SMARCA2; RBM14; PRKDC; MAFB; WWTR1; HLTF; NRBF2; HTATIP2; FOSL2; RBBP4; KLF6; PIR; NFIB; ZNF226; SUB1; CBFB; SPEN; SHOX2; USP22; PTTG1; BMI1; SOX9; RFX5; DAXX; NR1H2; WT1; CREG1; DMTF1; KDM5D; ZIC1; ETS1