Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09363	Osimertinib	GSE70138	HA1E	Human	24h	10uM	EID0036

Response Information :

Types	Number	Response transcription factors
Up-regulation	38	HMGA2; TSC22D3; FOSL1; FOXO4; SREBF2; HBP1; TSC22D1; ZNF83; DEAF1; NONO; ID2; PCGF2; HMGB3; TRIM16; NPAS2; DDIT3; ERBB2; FOXJ3; STAT1; EMX2; RBPJ; ATF1; MNDA; PHF20; SUZ12; DAXX; MXI1; TP53; USP22; NFE2L2; HOXC6; BTG1; PIR; MAFB; ZNF131; INSR; RFX5; HMG20B
Down-regulation	65	XBP1; RUVBL1; SFPQ; MYBL2; MLXIP; ILF2; WDR77; JUN; FOXM1; C1QBP; SIM2; GABPB1; HIPK1; PREB; KAT2B; TCF4; NFE2; SOX10; DR1; PTRF; ZNF140; NKX2-2; MAF; ELF5; TCF21; MEIS2; ZBTB20; CCNA2; LMCD1; AEBP1; GATA1; LEF1; NR5A2; EYA1; RUNX1; TGFB1; NHLH1; GRHL2; SMAD1; MYB; IRF4; ISL1; TFAP2C; ZNF589; EHF; CBFA2T3; ZFPM2; FOXF1; ID4; FOXF2; ZMYM2; SSX1; STAT3; ID3; NANOG; POU2AF1; PDLIM1; KLF7; KLF9; SUB1; TRPS1; SSBP2; CREB1; GLI2; MYBL1