Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09311 Ibrutinib GSE70138 HA1E Human 24h 1.11uM EID0036
Types Number Response transcription factors
Up-regulation 205 PBX1; PRRX1; HMBOX1; ZNF562; ZNF696; DYRK1B; PPARD; CDX2; PGR; HIRA; MBD1; ZNF500; KLF13; TGIF2; ZNF248; THRAP3; MED20; ZKSCAN4; ZNF223; ZNF219; MEOX1; POU5F1B; REL; ZKSCAN1; HDAC11; IRF5; HINFP; ZNF160; BANP; TWIST1; RING1; IRF8; CLOCK; ZNF189; ZFHX2; CDX1; ZNF124; HNF4G; ASH1L; PNRC1; CBX6; HOXB13; CDYL; SOX15; EP300; TFEB; TCF4; SPDEF; BARX1; CTNNB1; RXRG; PSMC3; HAND2; SALL2; ZNF512B; HOXC4; TULP3; MED14; SPIB; CAMTA2; RXRB; ARID3A; ERBB4; NR5A2; PLAGL1; SLC2A4RG; NFATC4; CUX2; LYL1; ZSCAN9; ZNF250; LZTR1; TAF1C; SETDB1; ZBTB16; SOX3; ZNF44; NCOA3; CHD4; CDC5L; ZNF345; FOXA2; HSF1; CBX2; TGFB1I1; PRDM1; HOXC8; CDIP1; OVOL1; POLR3C; HOXA3; TCF7L1; CHD9; RBM39; SOHLH2; PRDM14; GATA1; TRPS1; ZBTB20; ATOH1; GTF2I; ZIC3; ZNF629; ALX3; TDP2; HIC2; TCF7; ZNF623; ATN1; ZNF74; MAP3K10; TSC22D1; MXD4; KLF9; AIRE; ESR1; PBXIP1; BCL11A; EYA1; TLX3; MED15; NANOG; FOXG1; CBX4; INSM1; ZNF257; DACH1; VPS72; ZNF768; ZNF75D; SRCAP; THRB; MYCN; EMX1; TP73; PROX1; ERF; RBFOX2; TLE2; SUPT3H; BNC1; RAD21; ZNF606; HOXD11; CCNH; PITX3; NHLH1; ZNF778; ZNF573; LHX3; KDM5C; NR2F6; HLX; NRIP1; LIN28A; CBFA2T3; SOX21; PAX6; NFIC; CREBL2; TOX3; SMARCA1; NFE2L2; ST18; ZNF232; MEIS1; CREM; NEUROD1; KLF7; NFKB2; TCEA1; RARG; ZNF264; ZFP36L2; NKX2-1; FOXF2; ZNF91; ZNF665; ZNF165; SSBP3; MYRF; MAF; FOXF1; EPAS1; ELF4; MKL2; IRF9; ZIC1; GLI2; ZNF117; ZNF423; IRF6; CALR; HOXD1; SMAD1; TFAP2A; TP53; SNAI2; TXNIP; BNC2; TCFL5; ID1; SSBP2; MEIS2; TRIB3
Down-regulation 109 PSMD9; ZFP36L1; FHL2; NFKBIA; YBX3; CTBP1; CEBPG; HMGB2; FOXC1; KLF2; CCDC59; ZNF528; ATF4; NFYB; TBPL1; REST; TTF1; PAX8; WWC1; FOSL1; MYC; ZNF83; PHF8; NCOA4; FOXM1; CCNE1; DDIT3; CREB3L1; ANKRD1; NKX3-1; SETD2; NFYC; ZBTB18; DRAP1; RNF10; NFIB; UBE2B; FOSB; HMGA2; IRF2; SERTAD2; PHF2; TBL1X; MTDH; FOSL2; HSF2; SF1; EDF1; SMARCA4; THAP1; ZNF468; ECD; HOXB7; TRIM28; CHD7; CRY1; ATF7IP; BHLHE41; TAF7; TRRAP; EZH2; HOXB6; SMARCD3; ELF5; CTR9; PRKDC; SPEN; HTATIP2; DNAJC2; SMARCA2; KDM5D; NELFB; ZBED4; TRIP6; ZNF226; BAZ1A; NFE2L3; RBM14; HMGA1; CITED2; NR1D2; NR2F2; FLNA; MNDA; MED1; HOXB2; SMAD2; YWHAB; PIR; TBL1XR1; ZBTB38; SUB1; SCAND1; CREG1; FOS; MBD2; PUF60; LMCD1; ZFPM2; NR1H2; BTG1; FOXJ3; PBX3; BMI1; MAGED1; WT1; WWTR1; HOXC6; EGR2