Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09225 Idelalisib GSE70138 HA1E Human 24h 1.11uM EID0035
Types Number Response transcription factors
Up-regulation 76 MAFG; MYB; NRIP1; YBX2; NR3C1; NR4A1; MTF1; FOXJ3; STAT6; UIMC1; ZNF331; CBX5; ZNF444; TCEB2; WT1; SMAD7; SMAD2; PGR; INSR; NFIL3; EGR2; TBL1XR1; FLI1; IRF8; MEF2A; ARID4B; TRIM32; FOXD1; JARID2; SOX17; TFEC; CUX1; IRF2; IRF4; KDM5B; INSM1; HMGA1; CBX7; ETV5; FOSL2; NR4A2; HOXA11; TRIM28; TAL1; SP2; CEBPB; AFF1; TLE4; TCF7; NKX2-2; SSX1; HOXA10; TLE2; BATF3; RUNX3; PDLIM1; ZNF226; BNC2; PLAGL1; PTTG1; MYRF; TRIM16; NKX2-1; SIAH2; BHLHE41; NR1D2; ZNF131; HIRA; MEIS1; ETS1; IKBKAP; NEUROD1; FLNA; EGR3; ZFPM2; MNDA
Down-regulation 70 ZNF91; THAP11; CCNC; TFAM; ZNF12; NFIB; ARRB1; TXNIP; ZZZ3; PSMC3; CENPB; MED21; ID3; FOXO3; SMARCA4; E2F5; ZMYND8; ZNF430; TCEA1; CNBP; WWTR1; BRD2; ZNF593; XRCC6; TEAD4; ZNF232; PQBP1; HSBP1; PTRF; ZNF140; MEOX1; HOXA1; PBX3; ID4; TCF7L1; ZNF93; ZSCAN9; TFAP2A; EYA1; ELK3; FOXG1; RNF138; CREB5; CREB1; FOXO1; YBX3; TRIM29; TRIP6; HMGB1; EHF; SMAD1; IRX5; ZIC1; SIX1; ING3; NFIC; NR2F2; SNAI2; POU2AF1; MEIS2; CBFB; ENO1; TRPS1; HOXB6; NFATC4; MAFB; BCL11A; STAT1; SOX9; ZNF274