Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09199	Osimertinib	GSE70138	HA1E	Human	24h	10uM	EID0035

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	TSC22D3; IRF3; IRF9; IRF7; TRIM22; FOXO4; ZNF267; TFEC; CBX7; NPAS2; CXXC1; STAT2; LPIN2; HBP1; POU5F1B; AHR; HOXA7; MAFF; MAFB; HOXA5; ZNF432; PBXIP1; TGIF1; SP100; BACH1; STAT1; RBM39; PAX8; RXRA; ID2; PHF1; NR1H2; SALL1; KLF11; HMG20B; TXNIP; ZNF468; SPEN; STAT6; ZNF91; PIR; TP53; BTG1; ZNF331; ZNF665; ZNF217; SP110; MXI1; MYRF; AFF1; ZBTB1; ETV5; SCAND1; HOXB6; TCF7L2; HTATIP2; ATF5; MED13; KLF9; ERBB2; MYCL; NR2F6; ID4; ZBTB18; SOX9; PCGF2; HOXB2; ZNF589; ID3; ERBB4; ID1; IRF6
Down-regulation	79	GTF3A; JUN; MTDH; COPS5; PHOX2B; PITX1; FOXM1; PTRF; GABPB1; SMARCC2; CCNA2; ABL1; C1QBP; ISL1; YBX1; ELF5; GTF2A2; MLXIP; TRIP4; NFE2; POU2AF1; BTF3; SMARCA1; ZNF148; MEOX2; SF1; SOX11; EHF; ZBED4; YWHAB; DNAJC2; SMAD7; CEBPG; HMGB1; TGFB1I1; IRF4; ZIC1; CALR; IKBKAP; HAND1; EYA1; SSRP1; ZBTB16; RAD21; HOXB13; SIX1; TWIST1; BAZ1A; MAGED1; NFIC; SMAD1; HLTF; DMTF1; ERG; SLC2A4RG; FOXA2; PTTG1; IRX5; ZNF652; NKX3-1; MEIS2; FOSB; CREB1; ZMYM2; BCL11A; SNAI2; KDM5D; ZNF281; FOXA1; MECOM; ZBTB38; PAX6; TCF21; RFX5; TRPS1; ESR1; PEG3; ZNF274; SSBP2