Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09191 Motesanib GSE70138 HA1E Human 24h 0.37uM EID0035
Types Number Response transcription factors
Up-regulation 223 TBX1; GLI2; ZNF573; PAXBP1; MBD4; RAD21; SIX6; ZNF235; FOXI1; LHX2; ZNF500; PRRX1; AIRE; ZNF345; POU3F4; MAPK8IP1; VPS72; INSM1; NR0B2; TONSL; CBFA2T3; ZNF550; ZBED1; E2F8; ARID3A; DLX2; NR1I3; HMBOX1; FOXF2; NR5A2; ELF4; SOX13; STAT4; MAP3K10; ZNF79; PITX2; RFX2; ZNF623; PROX1; PRDM9; ZNF778; NR2F6; NEUROG2; HOXB8; ONECUT1; ZNF440; MLLT1; ZNF225; GATA6; MED25; HOXC13; SOX14; ZKSCAN4; SSBP3; THRB; CBX2; MED17; NHLH2; ZNF324; NHLH1; SUPT6H; MAML1; SOX18; ZNF665; TTF2; CD3D; GFI1; HOXC8; FOXA2; KDM5C; TFDP3; FEZF2; ZNF557; DLX4; HIC2; POU6F2; ZNF257; CHD2; ZNF415; NR5A1; PROP1; NFATC4; BARX1; LDB1; HOXD1; TEAD3; TRIM24; ZNF250; TFAP2A; TULP1; TP73; TBX10; TCFL5; ZNF669; SNAPC4; GBX2; GATA1; HLX; BRWD1; NPAS1; PNRC1; ZNF215; TCF7; SCRT1; SMARCB1; ALX3; OVOL1; ARID3B; ALX4; EN1; ATOH1; ZNF223; PRRX2; TEF; ZNF93; POU4F3; NEUROD1; ATF5; CDX2; ZNF74; PRDM14; ZNF232; ZNF544; LHX3; NEUROD2; VGLL1; ZNF141; TLX3; CDIP1; ACTL6B; MED14; ZNF211; SRY; ZNF154; PRDM2; SOX21; EMX1; GATA4; PITX3; ZNF75D; IRF6; ZNF682; ZIC1; OLIG2; ZNF701; BCL11A; EPAS1; CDX1; NFKB2; ATF3; ZNF91; RARG; ZNF85; ZNF117; SOX3; ZNF44; NCOA3; SIX3; HOXD3; ZNF160; SUPT3H; OSR2; KLF3; ZIC3; RUNX1; ZMIZ1; CBFA2T2; MAF; BACH2; ZNF266; TRIB3; TLE2; HES1; ZIM2; SPIB; AEBP1; ERBB4; TP63; PEG3; LIN28A; ID1; ST18; TDP2; JUP; BNC1; LYL1; ZNF611; ZFP36L2; MEIS2; NKX2-2; CEBPD; ELF3; PAX6; NANOG; MYBL1; IRF9; TCF7L2; SOX2; OVOL2; GRHL2; ARNT2; ZFPM2; SPDEF; POU2AF1; ZNF423; MYCL; LITAF; HEY1; TRPS1; ASCL1; NFE2L2; ID3; HIRA; FOXF1; NR4A2; TFAP2C; ZBTB16; NR0B1; TOX; TOX3; MYRF; SNAI2; STAT1
Down-regulation 78 BASP1; WWC1; ADNP2; SAP30; SMAD2; DRAP1; RYBP; ITGB3BP; BBX; ZNF532; TRIP6; PCBD1; PIAS2; BAZ1B; CCDC59; GABPB1; BTG1; ZBTB38; MED24; KAT7; SUB1; MED1; AFF1; IRF2; PAX8; TRRAP; TAF10; PCGF2; RNF10; JARID2; HNRNPD; NELFB; TBL1XR1; PUF60; MYCBP; MBD2; ELF1; TBL1X; ERBB2; PTTG1; GATAD2A; RFX5; NR2F2; TMF1; BCL3; SMARCA2; NUP62; TRIM16; NKX3-1; RBBP4; ELK3; SCAND1; FOXC1; KDM5D; BHLHE40; ING3; PDLIM1; DNAJC2; EDF1; CTR9; FLNA; ZMYM2; NFIB; HOXC6; ETS1; NR1H2; MAGED1; FOSL2; SMAD3; HMGB2; NR1D2; PIR; CREG1; ZBTB18; MSX1; CREB1; ZNF274; MTA1