Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09174 Gsk-1059615 GSE70138 HA1E Human 24h 0.12uM EID0035
Types Number Response transcription factors
Up-regulation 418 PPARD; PHIP; DACH1; REL; HOXA3; ZNF91; ZNF331; CALCOCO1; HES1; DLX2; ZNF224; ERBB4; MED25; SSBP3; ZNF175; ZNF665; ZBED1; IRF3; TCFL5; SALL2; KDM5C; TAF1; SIX6; HMX1; INSM1; PMS1; ARID3A; CLOCK; TONSL; KLF13; ZFHX2; PIAS4; HOXA6; TBX1; TULP3; PROP1; MED14; VPS72; BARX1; MECP2; RAD21; ZKSCAN4; ETV3; ZBTB7A; TCF7; TOX4; ZNF430; HBP1; TBX3; AIRE; FOXH1; ZNF358; HOXD1; ZNF335; SUPT7L; CDIP1; MBD3; ZKSCAN1; CEBPE; PNRC1; ZNF235; MAP3K10; KAT6A; NR0B2; ASH1L; L3MBTL1; SIX3; SRCAP; BRWD1; ZNF117; RFX1; LMX1B; ZNF646; HEYL; ZNF611; ZNF550; MED15; CARF; HSF4; SMARCB1; NHLH1; ZNF573; ZNF362; TRPS1; HNF1A; NR4A1; ZNF205; ZIC3; TGFB1; SOX13; LZTR1; CDX1; HR; TAF9B; CHD9; FOXF2; ZNF345; ZNF500; POU6F1; TFAP2A; ZBTB44; ZNF79; ZNF444; ADRB2; EVX1; HINFP; INSR; GLI1; PRRX1; JUP; FUBP1; MAML3; NEUROD1; PPARG; PCGF3; ZNF75D; CRX; TBX5; ZNF415; ST18; NR4A2; DYRK1B; NR6A1; NANOG; CHD2; NR5A1; TRIM25; CNOT3; NRL; FEZF2; ZBTB20; HOXA7; ZNF701; THRA; EMX1; EZH1; SMAD4; HIF3A; TUB; PRDM10; TCF3; ARID3B; CAMTA1; TEAD3; TCEA2; TFAP4; LDB1; FOXG1; ONECUT1; PRDM14; ZNF219; DLX4; BAZ2B; BCL11A; SMARCD3; HOXD3; NFE2; TAF1C; HDAC5; CBFA2T3; LHX3; SOX17; ZNF165; PAX6; ZNF778; NPAS1; ZNF264; FOXI1; NEUROG1; MKL2; FOXA2; NHLH2; ZNF223; E2F5; APBB1; PFDN5; ZNF83; NFYA; ZNF671; ATF6; PGR; ZNF160; NCOA3; FOXJ1; CCNH; RORC; DOT1L; DMTF1; PRDM1; ZNF688; GFI1; SKIL; HOXC4; HOXC13; LYL1; SCAI; SOX3; ZNF214; GATA1; IRF8; ZNF467; ZNF154; HEY1; TBX10; ZNF141; VAX2; CHD8; ACTL6B; LIN28A; HOXC5; CBX4; HDAC11; MEIS2; KAT2A; ARL2BP; TDP2; SOHLH2; ZNF33B; SCRT1; E2F4; ZKSCAN3; ZNF721; KLF3; NR2E1; PROX1; NKX6-1; SRY; TBR1; ZSCAN31; SIRT2; CBFA2T2; ZNF232; PAX7; ALX3; ZBTB3; SPIB; MAK; SOX21; SOX18; CDX2; SUPT3H; IRF9; MAML1; PITX3; NR2F6; ZNF225; SNAPC4; MLXIPL; ZNF133; TFDP3; HOXB8; CREM; ZNF195; ZNF24; ZNF623; NRIP1; EPAS1; BNC1; TWIST1; ZNF669; OVOL1; RFX2; HIPK2; ALX4; ATF5; ZFHX3; POU6F2; TP73; MBD1; NEUROD2; HLX; ZNF44; MEIS1; SETDB1; CDC5L; THRB; TULP1; SUZ12; NAB1; KLF7; CEBPD; TULP2; JUND; BRDT; E4F1; ZNF253; ZNF440; ATF3; SOX14; RARG; HDAC7; HMBOX1; BANP; ZXDC; POU5F1B; MYBL1; ZNF124; ZSCAN9; SOX2; MYCL; HOXB13; DLX5; ZNF557; ZNF74; NEUROG2; CBX2; POLR3C; TTF2; IRX4; SMAD7; SOX15; PRDM12; TULP4; IRF6; FOXF1; ZNF85; ZSCAN18; ATOH1; ZNF423; STAT4; NR5A2; RBFOX2; TERF1; POU4F3; WNT4; NFKB2; PBXIP1; RBM39; NEUROD6; SPI1; HOXB1; ZNF93; NKX2-1; ZIC1; NAB2; GBX2; KDM5B; ELF3; TLE2; TLX3; ZNF350; E2F8; CREB3L2; PRDM2; CERS4; NR0B1; NKX2-2; PRRX2; TLE4; NFATC4; MED12; ZBTB16; KLF9; ARID5B; SMAD1; TP63; AR; PBX3; ELF4; HIC2; AEBP1; GATA2; TRIB3; ZBED2; SPDEF; ZNF652; NFE2L2; ID1; NFATC3; FOXN3; HDAC9; TCF7L2; ZIM2; MYRF; NFAT5; OVOL2; PBX1; CUX2; MTF2; ZMIZ1; KMT2A; HOXA5; ESR1; ID3; CEBPB; SNAI2; LITAF; ID4; NCOA2; CD3D; IRX5; HIRA; GRHL2; TP53; BACH2; ZHX2; GLI2; TGIF1; STAT3; ZFPM2; CUX1; TCF4; OSR2; PEG3; FOXA1; SOX9; TCEA1; CITED2; ASCL1; EN1; GATA6; CRYM; ETS1; CREB1; NR1H2; TFAP2C; STAT1; SSBP2
Down-regulation 112 BASP1; PAX8; PUF60; FOSL1; DRAP1; SMARCE1; FHL2; ZFP36L1; SUB1; SAP30; KDM5D; PCBD1; MBD2; SMARCA4; ATF4; PIAS2; ELK3; RNF10; SAP18; WWC1; NFIL3; DNAJC2; XBP1; FOXO3; GABPB1; WWTR1; FOSL2; SETD2; YWHAB; KDM2A; PREB; CTR9; HNRNPD; TFDP1; XRCC6; TBPL1; NFKBIA; NUP62; MTDH; HOXB7; ZEB2; ZMYM2; RBM14; RFX5; NR2F2; MAGED1; HTATIP2; PSPC1; RBPMS; CRY1; C1QBP; DNMT3B; IRF4; ZBTB38; TBL1X; SNW1; USP22; ECD; ENO1; NKX3-1; TAF10; ING2; TRIP6; CBFB; HLF; PIAS3; TEAD4; NCOA4; IRF2; CCDC59; MED24; HMG20B; BATF3; BHLHE40; EDF1; TRIM32; ELF1; ELK1; PIR; MED6; PTTG1; BMI1; RUVBL2; TRIM28; ZMIZ2; ZNF131; CBX3; KAT7; TFAM; RUNX3; UBP1; ID2; HSF2; JARID2; AFF1; MSX1; FLNA; MYCBP; ZNF226; HLTF; PCGF2; PDLIM1; TRIM16; SIAH2; ZNF274; HMGB2; HOXC6; BHLHE41; CREG1; ZBTB18; FOXC1; SUV39H1